Yifan Han
Affiliations: | Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong |
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Publications
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| Mak S, Li W, Fu H, et al. (2021) Promising tacrine/huperzine A- based dimeric AChE inhibitors for neurodegenerative disorders: from relieving symptoms to modifying diseases through multi-target. Journal of Neurochemistry |
| Chen Q, Tu Y, Mak S, et al. (2020) Discovery of a novel small molecule PT109 with multi-targeted effects against Alzheimer's disease in vitro and in vivo. European Journal of Pharmacology. 173361 |
| Lu J, Chen C, Deng X, et al. (2020) Design, synthesis, and biological evaluation of novel multifunctional Rolipram-Tranilast hybrids as potential treatment for traumatic brain injury. Acs Chemical Neuroscience |
| Hu S, Xian Y, Fan Y, et al. (2020) Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer's agent. European Journal of Pharmacology. 173065 |
| Liu Z, Qiu X, Shinghung MAK, et al. (2020) Multifunctional memantine nitrate significantly protects against glutamate-induced excitotoxicity via inhibiting calcium influx and attenuating PI3K/Akt/GSK3beta pathway. Chemico-Biological Interactions. 109020 |
| Mak S, Liu Z, Wu L, et al. (2020) Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in vitro and in vivo. Acs Chemical Neuroscience |
| Zuo X, Hu S, Tang Y, et al. (2019) Attenuation of secondary damage and Aβ deposits in the ipsilateral thalamus of dMCAO rats through reduction of cathepsin B by bis(propyl)-cognitin, a multifunctional dimer. Neuropharmacology. 107786 |
| Li HQ, Ip SP, Yuan QJ, et al. (2019) Isorhynchophylline Ameliorates Cognitive Impairment via Modulating Amyloid Pathology, Tau Hyperphosphorylation and Neuroinflammation: Studies in a Transgenic Mouse Model of Alzheimer's Disease. Brain, Behavior, and Immunity |
| Luo F, Wu L, Zhang Z, et al. (2019) A dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid hemorrhage models. British Journal of Pharmacology |
| Chen H, Wu X, Gu X, et al. (2018) Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice. Frontiers in Cellular Neuroscience. 12: 396 |