Christine E. Holt

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
Axon growth and guidance
Website:
http://www.pdn.cam.ac.uk/staff/holt/index.html
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"Christine Holt"
Mean distance: 13.75 (cluster 11)
 
SNBCP

Parents

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John Scholes grad student UCL
William A. Harris post-doc 1981-1985 UCSD

Children

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Douglas S. Campbell grad student RIKEN Brain Science Institute, Wako, Saitama, Japan
Louis Leung grad student Cambridge
Julie Qiaojin Lin grad student Cambridge
Benita Turner-Bridger grad student Cambridge
Karl G. Johnson grad student 1997-2000 Cambridge
Andrew C. Lin grad student 2004-2009 Cambridge
Hovy Ho-Wai Wong grad student 2012-2016 Cambridge
Roberta Cagnetta grad student 2013-2018 Cambridge
Jean-Michel Cioni post-doc
Shinichi Kakagawa post-doc Cambridge
Barbara Lom post-doc UCSD
Sarah McFarlane post-doc UCSD
Shin-ichi Ohnuma post-doc Cambridge
Catherine M. O'Hare (Massaro) post-doc 2010- Cambridge
Max Koppers post-doc 2016-
Fanny Mann post-doc 2000-2003 IBDML
Kristian Franze post-doc 2007-2011
Marie-Laure Baudet post-doc 2007-2012 Cambridge
Hovy Ho-Wai Wong post-doc 2016-2017 Cambridge
Roberta Cagnetta post-doc 2018-2019 Cambridge
BETA: Related publications

Publications

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Holt CE. (2024) Biological Roles of Local Protein Synthesis in Axons: A Journey of Discovery. Annual Review of Genetics
Tartwijk FWV, Wunderlich LCS, Mela I, et al. (2024) Mutation of the ALS/FTD-associated RNA-binding protein FUS affects axonal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Clifton NE, Lin JQ, Holt CE, et al. (2023) Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder. Biological Psychiatry
Jung J, Ohk J, Kim H, et al. (2022) mRNA transport, translation, and decay in adult mammalian central nervous system axons. Neuron
Koppers M, Holt CE. (2022) Receptor-Ribosome Coupling: A Link Between Extrinsic Signals and mRNA Translation in Neuronal Compartments. Annual Review of Neuroscience
Lu M, van Tartwijk FW, Lin JQ, et al. (2020) The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes. Science Advances. 6
Lin JQ, van Tartwijk FW, Holt CE. (2020) Axonal mRNA translation in neurological disorders. Rna Biology. 1-26
Farias J, Holt CE, Sotelo JR, et al. (2020) Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons. Rna (New York, N.Y.)
Shigeoka T, Koppers M, Wong HH, et al. (2019) On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons. Cell Reports. 29: 3605-3619.e10
Koppers M, Cagnetta R, Shigeoka T, et al. (2019) Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. Elife. 8
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