Bianca M. Liederer, Ph.D.

Affiliations: 
2005 University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry, Pharmacy
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Ronald T. Borchardt grad student 2005 University of Kansas
 (Prodrug strategies for improving oral and blood -brain barrier delivery of opioid peptides.)
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Publications

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Chan P, Ding HT, Liederer BM, et al. (2021) Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor. Clinical and Translational Science
Hamilton GL, Chen H, Deshmukh G, et al. (2019) Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group. Bioorganic & Medicinal Chemistry Letters
Liederer BM, Cheong J, Chou KJ, et al. (2018) Preclinical Assessment of the ADME, Efficacy and Drug-Drug Interaction Potential of a Novel NAMPT Inhibitor. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-56
Daemen A, Liu B, Song K, et al. (2018) Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State. Cell Metabolism
Durk MR, Deshmukh G, Valle N, et al. (2018) Use of Subcutaneous and Intraperitoneal Administration Methods to Facilitate Cassette Dosing in Microdialysis Studies in Rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Liang J, Labadie S, Zhang B, et al. (2017) From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorganic & Medicinal Chemistry Letters
Wong H, Bohnert T, Damian-Iordache V, et al. (2017) Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective. Drug Discovery Today
Misner DL, Kauss MA, Singh J, et al. (2016) Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines. Cardiovascular Toxicology
Zak M, Yuen PW, Liu X, et al. (2016) Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. Journal of Medicinal Chemistry
Liang J, Zhang B, Labadie S, et al. (2016) Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies. Bioorganic & Medicinal Chemistry Letters
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