Lucas Pozzo-Miller, Ph.D.

1998- Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 
Synapses, BDNF, MeCP2, Rett Syndrome

Lucas Pozzo-Miller completed his undergraduate studies in Biology (MSc, 1986) and earned his graduate degree from the Universidad Nacional de Córdoba, Argentina (PhD, 1989). He trained as postdoctoral fellow at Case Western Reserve University, Cleveland OH, with Dennis Landis (1990-1992), and at the Roche Institute of Molecular Biology, Nutley NJ, with John Connor (1992-1995). He performed research at the Marine Biological Laboratory, Woods Hole MA, with Rodolfo Llinás (1994 Grass Foundation Fellow, and 1995 Lakian Foundation Fellow). He was a Senior Staff Fellow at the National Institutes of Health, Bethesda MD, in the laboratory of Tom Reese (1995-1998). He joined the faculty of the Department of Neurobiology at The University of Alabama at Birmingham in 1998, and is presently Professor of Neurobiology, and Associate Director of the UAB Comprehensive Neuroscience Center.

Mean distance: 12.86 (cluster 6)


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Agustin Aoki grad student 1986-1989 Universidad Nacional de Cordoba
Dennis Landis post-doc 1990-1992 Case Western
John Connor post-doc 1992-1995 Hoffman-La Roche
Rodolfo R. Llinás post-doc 1994-1995 NYU
 (Summers at MBL, Woods Hole MA)
Thomas S. Reese post-doc 1995-1998 NINDS


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Mary  L. Phillips grad student 2013- UAB
Cesar A Acevedo-Triana grad student 2019-
William James Tyler grad student 1999-2003 UAB
Michelle D. Amaral grad student 2003-2008 UAB
Christopher A. Chapleau grad student 2003-2008 UAB
Wei Li post-doc 2010- UAB
Xin Xu post-doc 2011- UAB
Yong Li post-doc 2007-2010 UAB
Gaston Calfa post-doc 2007-2011 UAB
BETA: Related publications


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Carstens KE, Phillips ML, Pozzo-Miller L, et al. (2016) Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6312-20
Li W, Xu X, Pozzo-Miller L. (2016) Excitatory synapses are stronger in the hippocampus of Rett syndrome mice due to altered synaptic trafficking of AMPA-type glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America
Pozzo-Miller L, Pati S, Percy AK. (2015) Rett Syndrome: Reaching for Clinical Trials. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 631-40
Wang H, Pati S, Pozzo-Miller L, et al. (2015) Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes. Frontiers in Cellular Neuroscience. 9: 55
Phillips M, Pozzo-Miller L. (2015) Dendritic spine dysgenesis in autism related disorders. Neuroscience Letters. 601: 30-40
Calfa G, Li W, Rutherford JM, et al. (2015) Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice. Hippocampus. 25: 159-68
Xu X, Miller EC, Pozzo-Miller L. (2014) Dendritic spine dysgenesis in Rett syndrome. Frontiers in Neuroanatomy. 8: 97
Xu X, Kozikowski AP, Pozzo-Miller L. (2014) A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome. Frontiers in Cellular Neuroscience. 8: 68
Li W, Pozzo-Miller L. (2014) BDNF deregulation in Rett syndrome. Neuropharmacology. 76: 737-46
Calfa G, Percy AK, Pozzo-Miller L. (2014) Dysfunction of the methyl-CpG-binding protein MeCP2 in rett syndrome Patho-Epigenetics of Disease. 43-69
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