Koen Jansen, Ph.D.
Affiliations: | 2014 | Universiteit Antwerpen (Belgium) |
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Sign in to add mentor| I De Meester | grad student | 2014 | Universiteit Antwerpen (Belgium) | |
| (Potent and selective inhibitors of fibroblast activation protein (FAP).) | ||||
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| De Decker A, Vliegen G, Van Rompaey D, et al. (2019) Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP). Acs Medicinal Chemistry Letters. 10: 1173-1179 |
| Heirbaut L, Van Goethem S, Jansen K, et al. (2016) Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: The impact of P1-variation Medchemcomm. 7: 433-438 |
| Jansen K, Heirbaut L, Verkerk R, et al. (2014) Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP) Journal of Medicinal Chemistry. 57: 3053-3074 |
| Jansen K, De Winter H, Heirbaut L, et al. (2014) Selective inhibitors of fibroblast activation protein (FAP) with a xanthine scaffold Medchemcomm. 5: 1700-1707 |
| Jansen K, Heirbaut L, Cheng JD, et al. (2013) Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold. Acs Medicinal Chemistry Letters. 4: 491-6 |
| Ryabtsova O, Jansen K, Van Goethem S, et al. (2012) Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity. Bioorganic & Medicinal Chemistry Letters. 22: 3412-7 |