Joseph A. Wawrzyniak, Ph.D.
Affiliations: | 2014 | Roswell Park . Biophysics | State University of New York, Buffalo, Buffalo, NY, United States |
Area:
Genetics, BiochemistryGoogle:
"Joseph Wawrzyniak"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mikhail Nikiforov | grad student | 2014 | SUNY Buffalo | |
| (Guanosine Monophosphate Reductase (GMPR) is a Suppressor of Melanoma Invasion.) | ||||
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Publications
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| Bagati A, Bianchi-Smiraglia A, Moparthy S, et al. (2017) Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. Cell Reports. 20: 2820-2832 |
| Bianchi-Smiraglia A, Bagati A, Fink EE, et al. (2016) Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools. Oncogene |
| Bianchi-Smiraglia A, Wawrzyniak JA, Bagati A, et al. (2015) Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity. Cell Death and Differentiation |
| Zucker SN, Fink EE, Bagati A, et al. (2014) Nrf2 amplifies oxidative stress via induction of Klf9. Molecular Cell. 53: 916-28 |
| Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, et al. (2013) A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion. Cell Reports. 5: 493-507 |
| Mannava S, Moparthy KC, Wheeler LJ, et al. (2012) Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion. Aging. 4: 917-22 |
| Zucker SN, Zirnheld J, Bagati A, et al. (2012) Preferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch. Cancer Biology & Therapy. 13: 1299-306 |
| Mannava S, Zhuang D, Nair JR, et al. (2012) KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells. Blood. 119: 1450-8 |
| Mannava S, Omilian AR, Wawrzyniak JA, et al. (2012) PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells. Oncogene. 31: 1484-92 |
| Zhuang D, Mannava S, Grachtchouk V, et al. (2008) C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells. Oncogene. 27: 6623-34 |