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Jiakang Sun, Ph.D.

Affiliations: 
2011 Biochemistry and Molecular Biology Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States 
Area:
Biochemistry, Molecular Biology
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"Jiakang Sun"
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Ronald S. Kaplan grad student 2011 Rosalind Franklin Medical School
 (Functional Studies with the Plasma Membrane and the Mitochondrial Citrate Transport Proteins.)

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Publications

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Sun J, Aluvila S, Kotaria R, et al. (2010) Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis. Molecular and Cellular Pharmacology. 2: 101-110
Aluvila S, Kotaria R, Sun J, et al. (2010) The yeast mitochondrial citrate transport protein: molecular determinants of its substrate specificity. The Journal of Biological Chemistry. 285: 27314-26
Mayor JA, Sun J, Kotaria R, et al. (2010) Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach. Journal of Bioenergetics and Biomembranes. 42: 99-109
Aluvila S, Sun J, Harrison DH, et al. (2010) Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor. Molecular Pharmacology. 77: 26-34
Kaplan RS, Mayor JA, Sun J, et al. (2010) Transport Inhibitors Cause Conformational Changes in the Yeast Mitochondrial Citrate Transport Protein Reconstituted in Liposomes as Demonstrated by EPR Spectroscopy Biophysical Journal. 98: 685a-686a
Sun J, Mayor JA, Kotaria R, et al. (2009) High-Yield Expression and Purification of a Plasma Membrane Citrate Transport Protein Biophysical Journal. 96: 686a
Remani S, Sun J, Kotaria R, et al. (2008) The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate. Journal of Bioenergetics and Biomembranes. 40: 577-85
Ma C, Remani S, Sun J, et al. (2007) Identification of the substrate binding sites within the yeast mitochondrial citrate transport protein. The Journal of Biological Chemistry. 282: 17210-20
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