MARIAN DIFIGLIA, PhD
Affiliations: | MASS GENERAL INSTITUTE FOR NEURODEGENERATIVE DISEASE | MASSACHUSSETS GENERAL HOSPITAL |
Area:
NEUROPATHOLOGYWebsite:
http://www.mghmind.org/Faculty/difiglia_marian.htmlGoogle:
"MARIAN DIFIGLIA"Mean distance: 20.71 (cluster 32)
Cross-listing: Neuropathology Tree
Children
Sign in to add trainee| Maria Iuliano | research assistant | 2014-2018 | MGH |
| ROSALINDA C. ROBERTS | post-doc | 1988-1990 | MASSACHUSSETS GENERAL HOSPITAL |
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Publications
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| O'Reilly D, Belgrad J, Ferguson C, et al. (2023) Di-valent siRNA Mediated Silencing of MSH3 Blocks Somatic Repeat Expansion in Mouse Models of Huntington's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Chhetri G, Ke Y, Wang P, et al. (2022) Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease. The Journal of Cell Biology. 221 |
| Iuliano M, Seeley C, Sapp E, et al. (2021) Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum. Frontiers in Synaptic Neuroscience. 13: 618391 |
| DiFiglia M. (2020) An early start to Huntington's disease. Science (New York, N.Y.). 369: 771-772 |
| Sapp E, Seeley C, Iuliano M, et al. (2020) Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region. Neurobiology of Disease. 141: 104950 |
| Wang X, Weng M, Ke Y, et al. (2020) Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling. Cells. 9 |
| Aviolat H, Pinto RM, Godschall E, et al. (2019) Assessing average somatic CAG repeat instability at the protein level. Scientific Reports. 9: 19152 |
| Li Z, Wang C, Wang Z, et al. (2019) Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature |
| Alterman JF, Godinho BMDC, Hassler MR, et al. (2019) A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. Nature Biotechnology. 37: 884-894 |
| Haraszti RA, Miller R, Dubuke ML, et al. (2019) Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition. Iscience. 16: 230-241 |