Karen O'Malley
Affiliations: | Anatomy and Neurobiology | Washington University, Saint Louis, St. Louis, MO |
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Children
Sign in to add trainee| Maria J. Lotharius | grad student | 2000 | Washington University |
| William A. Holtz | grad student | 2004 | Washington University |
| Daphne M. Hasbani | grad student | 2007 | Washington University |
| Alison I. Bernstein | grad student | 2003-2009 | Washington University |
| Jo Ann V. Antenor-Dorsey | grad student | 2011 | Washington University |
| Ismail Sergin | grad student | 2012 | Washington University |
| Carolyn A. Purgert | grad student | 2015 | Washington University |
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Publications
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| Jong YI, Izumi Y, Harmon SK, et al. (2023) Striatal mGlu-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways. The Journal of Biological Chemistry. 104949 |
| Jong YI, Harmon SK, O'Malley KL. (2019) Location and cell-type specific bias of metabotropic glutamate receptor, mGlu5, negative allosteric modulators. Acs Chemical Neuroscience |
| Sergin I, Jong YI, Harmon SK, et al. (2017) Sequences within the C-terminus of the metabotropic glutamate receptor, mGluR5, are responsible for inner nuclear membrane localization. The Journal of Biological Chemistry |
| Vincent K, Cornea VM, Jong YJ, et al. (2016) Intracellular mGluR5 plays a critical role in neuropathic pain. Nature Communications. 7: 10604 |
| Jong YJ, Sergin I, Purgert CA, et al. (2014) Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5. Molecular Pharmacology. 86: 774-85 |
| Purgert CA, Izumi Y, Jong YJ, et al. (2014) Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4589-98 |
| Bernstein AI, O'Malley KL. (2013) MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death. Toxicology Letters. 219: 93-8 |
| Burke RE, O'Malley K. (2013) Axon degeneration in Parkinson's disease. Experimental Neurology. 246: 72-83 |
| Kumar V, Fahey PG, Jong YJ, et al. (2012) Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein. The Journal of Biological Chemistry. 287: 5412-25 |
| Bernstein AI, Garrison SP, Zambetti GP, et al. (2011) 6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death. Molecular Neurodegeneration. 6: 2 |