Helen E. Scharfman

Affiliations: 
Columbia University, New York, NY 
Area:
Epilepsy
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"Helen Scharfman"
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Publications

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Lisgaras CP, Scharfman HE. (2022) Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice. Neurobiology of Disease. 166: 105637
Stephens GS, Fu CH, St Romain CP, et al. (2020) Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions. Frontiers in Neuroscience. 14: 472
Botterill JJ, Lu YL, LaFrancois JJ, et al. (2019) An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy. Cell Reports. 29: 2875-2889.e6
Fu CH, Iascone DM, Petrof I, et al. (2019) Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model. Cell Reports. 27: 3741-3751.e4
Luna VM, Anacker C, Burghardt NS, et al. (2019) Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus. Science (New York, N.Y.). 364: 578-583
Jain S, LaFrancois JJ, Botterill JJ, et al. (2019) Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures. Hippocampus
Scharfman HE, Kanner AM, Friedman A, et al. (2017) Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research? Epilepsy & Behavior : E&B
You JC, Muralidharan K, Park JW, et al. (2017) Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. Nature Medicine
Bermudez-Hernandez K, Lu YL, Moretto J, et al. (2017) Hilar granule cells of the mouse dentate gyrus: effects of age, septotemporal location, strain, and selective deletion of the proapoptotic gene BAX. Brain Structure & Function
Moretto JN, Duffy ÁM, Scharfman HE. (2017) Acute restraint stress decreases c-fos immunoreactivity in hilar mossy cells of the adult dentate gyrus. Brain Structure & Function
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