Jean-Charles Schwartz, Ph.D

"Jean-Charles Schwartz"
Mean distance: 16.65 (cluster 11)


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Jean Costentin grad student
Elisabeth Traiffort grad student
Bruno Giros grad student 1983-1987 INSERM, Paris
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Rusjan PM, Sabioni P, Di Ciano P, et al. (2020) Exploring Occupancy of the Histamine H3 Receptor by Pitolisant in Humans Using Positron Emission Tomography. British Journal of Pharmacology
Lecendreux M, Plazzi G, Franco P, et al. (2019) Pharmacokinetics of pitolisant in children and adolescents with narcolepsy. Sleep Medicine. 66: 220-226
Setnik B, McDonnell M, Mills C, et al. (2019) Evaluation of the abuse potential of pitolisant, a selective H3-receptor antagonist/inverse agonist, for the treatment of adult patients with narcolepsy with or without cataplexy. Sleep
Dauvilliers Y, Arnulf I, Szakacs Z, et al. (2019) Long-term use of pitolisant to treat patients with narcolepsy: Harmony III Study. Sleep
Thorpy M, Schwartz J, Lecomte J, et al. (2018) 0624 Anticataplectic Efficacy of Pitolisant, the First Potent and Highly Selective Histamine H3-Receptor Antagonist/Inverse Agonist Sleep. 41
Szakacs Z, Dauvilliers Y, Mikhaylov V, et al. (2017) Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial. The Lancet. Neurology
Levoin N, Labeeuw O, Billot X, et al. (2016) Discovery of nanomolar ligands with novel scaffolds for the histamine H4 receptor by virtual screening. European Journal of Medicinal Chemistry. 125: 565-572
Labeeuw O, Levoin N, Billot X, et al. (2016) Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists. Bioorganic & Medicinal Chemistry Letters
Schwartz JC, Lecomte JM. (2016) Clinical trials with H3-receptor inverse agonists: what they tell us about the role of histamine in the human brain. Neuropharmacology
Capet M, Calmels T, Levoin N, et al. (2015) Improving selectivity of dopamine D3 receptor ligands. Bioorganic & Medicinal Chemistry Letters
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