Sudarshana Purkayastha

Albert Einstein College of Medicine, USA 
NFkB pathway :cardiovascular & metabolic disorders
"Sudarshana Purkayastha"
Mean distance: 22.67 (cluster 59)
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Tang Y, Purkayastha S, Cai D. (2015) Hypothalamic microinflammation: a common basis of metabolic syndrome and aging. Trends in Neurosciences. 38: 36-44
Yan J, Zhang H, Yin Y, et al. (2014) Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response. Nature Medicine. 20: 1001-8
Li J, Tang Y, Purkayastha S, et al. (2014) Control of obesity and glucose intolerance via building neural stem cells in the hypothalamus. Molecular Metabolism. 3: 313-24
Purkayastha S, Cai D. (2013) Neuroinflammatory basis of metabolic syndrome. Molecular Metabolism. 2: 356-63
Cai D, Purkayastha S. (2013) A New Horizon: Oxytocin as a Novel Therapeutic Option for Obesity and Diabetes. Drug Discovery Today. Disease Mechanisms. 10: e63-e68
Purkayastha S, Cai D. (2013) Disruption of neurogenesis by hypothalamic inflammation in obesity or aging. Reviews in Endocrine & Metabolic Disorders. 14: 351-6
Zhang G, Li J, Purkayastha S, et al. (2013) Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature. 497: 211-6
Purkayastha S, Ford J, Kanjilal B, et al. (2012) Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions. Journal of Neurochemistry. 120: 396-407
Levano K, Punia V, Raghunath M, et al. (2012) Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning. Journal of Neurochemistry. 120: 302-13
Purkayastha S, Zhang G, Cai D. (2011) Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB. Nature Medicine. 17: 883-7
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