Sudarshana Purkayastha

Affiliations: 
Albert Einstein College of Medicine, New York, New York, United States 
Area:
NFkB pathway :cardiovascular & metabolic disorders
Google:
"Sudarshana Purkayastha"
Mean distance: 22.67 (cluster 59)
 
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Publications

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Tang Y, Purkayastha S, Cai D. (2015) Hypothalamic microinflammation: a common basis of metabolic syndrome and aging. Trends in Neurosciences. 38: 36-44
Yan J, Zhang H, Yin Y, et al. (2014) Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response. Nature Medicine. 20: 1001-8
Li J, Tang Y, Purkayastha S, et al. (2014) Control of obesity and glucose intolerance via building neural stem cells in the hypothalamus. Molecular Metabolism. 3: 313-24
Purkayastha S, Cai D. (2013) Neuroinflammatory basis of metabolic syndrome. Molecular Metabolism. 2: 356-63
Cai D, Purkayastha S. (2013) A New Horizon: Oxytocin as a Novel Therapeutic Option for Obesity and Diabetes. Drug Discovery Today. Disease Mechanisms. 10: e63-e68
Purkayastha S, Cai D. (2013) Disruption of neurogenesis by hypothalamic inflammation in obesity or aging. Reviews in Endocrine & Metabolic Disorders. 14: 351-6
Zhang G, Li J, Purkayastha S, et al. (2013) Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature. 497: 211-6
Purkayastha S, Zhang G, Cai D. (2011) Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB. Nature Medicine. 17: 883-7
Purkayastha S, Zhang H, Zhang G, et al. (2011) Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress. Proceedings of the National Academy of Sciences of the United States of America. 108: 2939-44
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