Jessica L. Keffer, Ph.D.
Affiliations: | 2012 | Biochemistry & Molecular | Georgetown University, Washington, DC |
Area:
Biochemistry, Microbiology Biology, Pharmaceutical ChemistryGoogle:
"Jessica Keffer"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Carole A. Bewley | grad student | 2012 | Georgetown | |
| (The structures, biological activity, and mechanistic studies of novel marine-derived antibacterial compounds.) | ||||
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Publications
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| Keffer JL, Huecas S, Hammill JT, et al. (2013) Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria. Bioorganic & Medicinal Chemistry. 21: 5673-8 |
| Keffer JL, Hammill JT, Lloyd JR, et al. (2012) Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments. Marine Drugs. 10: 1103-25 |
| Cheruku P, Plaza A, Lauro G, et al. (2012) Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor. Journal of Medicinal Chemistry. 55: 735-42 |
| Perera HD, Keffer J, Bewley C. (2012) The Mode of Action of FtsZ Inhibitors Biophysical Journal. 102: 64a |
| Cheruku P, Keffer JL, Dogo-Isonagie C, et al. (2010) Motualevic acids and analogs: synthesis and antimicrobial structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 20: 4108-11 |
| Plaza A, Keffer JL, Bifulco G, et al. (2010) Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ. Journal of the American Chemical Society. 132: 9069-77 |
| Plaza A, Bifulco G, Masullo M, et al. (2010) Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species. The Journal of Organic Chemistry. 75: 4344-55 |
| Plaza A, Keffer JL, Lloyd JR, et al. (2010) Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei. Journal of Natural Products. 73: 485-8 |
| Keffer JL, Plaza A, Bewley CA. (2009) Motualevic acids A-F, antimicrobial acids from the sponge Siliquariaspongia sp. Organic Letters. 11: 1087-90 |
| Plaza A, Bifulco G, Keffer JL, et al. (2009) Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry. The Journal of Organic Chemistry. 74: 504-12 |