Roger P. Leng, Ph.D.

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Wu H, Leng RP. (2015) MDM2 mediates p73 ubiquitination: A new molecular mechanism for suppression of p73 function Oncotarget. 6: 21479-21492
Abou Zeinab R, Wu H, Sergi C, et al. (2013) Residues 240-250 in the C-terminus of the Pirh2 protein complement the function of the RING domain in self-ubiquitination of the Pirh2 protein Plos One. 8
Bagashev A, Fan S, Mukerjee R, et al. (2013) Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein. Cell Cycle (Georgetown, Tex.). 12: 1569-77
Bagashev A, Fan S, Mukerjee R, et al. (2013) Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein Veterinary Record. 172: 1569-1577
Zeinab RA, Wu H, Sergi C, et al. (2012) UBE4B: A promising regulatory molecule in neuronal death and survival International Journal of Molecular Sciences. 13: 16865-16879
Johnston J, Al-Bahrani R, Abuetabh Y, et al. (2012) Twisted gastrulation expression in cholangiocellular and hepatocellular carcinoma Journal of Clinical Pathology. 65: 945-948
Wu H, Zeinab RA, Flores ER, et al. (2011) Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination Molecular Cancer Research. 9: 1780-1790
Wu H, Leng RP. (2011) UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation Cell Cycle. 10: 1912-1915
Wu H, Pomeroy SL, Ferreira M, et al. (2011) UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53. Nature Medicine. 17: 347-55
Argimón S, Wishart JA, Leng R, et al. (2007) Developmental regulation of an adhesin gene during cellular morphogenesis in the fungal pathogen Candida albicans. Eukaryotic Cell. 6: 682-92