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Varun Gauba, Ph.D.

Affiliations: 
2004-2009 Chemistry Rice University, Houston, TX 
 2009-2012 Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2012-2013 Protein Science aTyr Pharma 
 2013- Fuels Technology Shell 
Area:
Organic Chemistry, General Biophysics
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Parents

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Jeffrey D. Hartgerink grad student 2009 Rice University
 (Design, self -assembly and applications of heterotrimeric collagen mimics.)
Peter G. Schultz post-doc 2009-2012 Scripps Research Institute

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Publications

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Kessel C, Nandakumar KS, Peters FB, et al. (2014) A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 610-21
Gauba V, Grünewald J, Gorney V, et al. (2011) Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids. Proceedings of the National Academy of Sciences of the United States of America. 108: 12821-6
Fallas JA, Gauba V, Hartgerink JD. (2009) Solution structure of an ABC collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions. The Journal of Biological Chemistry. 284: 26851-9
Gauba V, Hartgerink JD. (2008) Synthetic collagen heterotrimers: structural mimics of wild-type and mutant collagen type I. Journal of the American Chemical Society. 130: 7509-15
Gauba V, Hartgerink JD. (2007) Surprisingly high stability of collagen ABC heterotrimer: evaluation of side chain charge pairs. Journal of the American Chemical Society. 129: 15034-41
Gauba V, Hartgerink JD. (2007) Self-assembled heterotrimeric collagen triple helices directed through electrostatic interactions. Journal of the American Chemical Society. 129: 2683-90
Paramonov SE, Gauba V, Hartgerink JD. (2005) Synthesis of collagen-like peptide polymers by native chemical ligation Macromolecules. 38: 7555-7561
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