Denis V. Titov
Affiliations: | Pharmacology and Molecular Sciences | Johns Hopkins University School of Medicine, Baltimore, MD, United States |
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Parents
Sign in to add mentor| Jun O. Liu | grad student | 2012 | UC Berkeley | |
| (Mechanism of action of the antiproliferative natural product triptolide.) | ||||
| Vamsi Mootha | post-doc | Harvard (Cell Biology Tree) | ||
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Publications
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| Choe M, Titov DV. (2023) Genetically encoded tool for manipulation of ΔΨm identifies the latter as the driver of integrative stress response induced by ATP Synthase dysfunction. Biorxiv : the Preprint Server For Biology |
| Mick E, Titov DV, Skinner OS, et al. (2020) Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. Elife. 9 |
| Mick E, Titov DV, Skinner OS, et al. (2020) Author response: Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell Elife |
| Cracan V, Titov DV, Shen H, et al. (2017) A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nature Chemical Biology |
| Titov DV, Cracan V, Goodman RP, et al. (2016) Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science (New York, N.Y.). 352: 231-5 |
| Lewis-Smith D, Kamer KJ, Griffin H, et al. (2016) Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood. Neurology. Genetics. 2: e59 |
| Cracan V, Titov D, Grabarek Z, et al. (2016) Genetically Encoded Tools for Compartment-Specific Manipulation of NAD+/NADH or NADP+/NADPH Ratios Free Radical Biology and Medicine. 100: S182 |
| He QL, Titov DV, Li J, et al. (2015) Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angewandte Chemie (International Ed. in English). 54: 1859-63 |
| Titov DV, Liu JO. (2012) Identification and validation of protein targets of bioactive small molecules. Bioorganic & Medicinal Chemistry. 20: 1902-9 |
| Titov DV, Gilman B, He QL, et al. (2011) XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature Chemical Biology. 7: 182-8 |