William S. Trimble

Affiliations: 
Biochemistry University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Biochemistry, v-SNARE, vesicle fusion, neurotransmitters
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"William Trimble"
Bio:

Second Chair of cell biology at SickKids after Sergio Grinstein and before John Brumell

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Parents

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Nobumichi Hozumi grad student 1987 (Cell Biology Tree)
 (mechanisms responsible for cellular transformation by the ras oncogene)
Richard Scheller post-doc 1990 Stanford
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Publications

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Safavian D, Kim MS, Xie H, et al. (2023) Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone. The Journal of Cell Biology. 222
Soroor F, Kim MS, Palander O, et al. (2020) Revised subunit order of mammalian septin complexes explains their in-vitro polymerization properties. Molecular Biology of the Cell. mbcE20060398
Palander O, Trimble WS. (2020) DIAPH1 regulates ciliogenesis and trafficking in primary cilia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Levin-Konigsberg R, Montaño-Rendón F, Keren-Kaplan T, et al. (2019) Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling. Nature Cell Biology
Heybrock S, Kanerva K, Meng Y, et al. (2019) Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nature Communications. 10: 3521
Marques PE, Nyegaard S, Collins RF, et al. (2019) Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane. Developmental Cell
Vissa A, Giuliani M, Froese CD, et al. (2018) Single-Molecule Localization Microscopy Of Septin Bundles in Mammalian Cells. Cytoskeleton (Hoboken, N.J.)
Boddy KC, Gao AD, Truong D, et al. (2018) Septin-regulated actin dynamics promote Salmonella invasion of host cells. Cellular Microbiology. e12866
Liu S, Ginzberg MB, Patel N, et al. (2018) Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length. Elife. 7
Stefan CJ, Trimble WS, Grinstein S, et al. (2017) Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. Bmc Biology. 15: 102
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