Jun Xu, Ph.D.

Affiliations: 
Neuroscience University of Iowa, Iowa City, IA 
Area:
Pain
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"Jun Xu"
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Publications

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McGaraughty S, Chu KL, Xu J. (2018) Characterization and Pharmacological Modulation of Noci-Responsive Deep Dorsal Horn Neurons Across Diverse Rat Models of Pathological Pain. Journal of Neurophysiology
Brederson JD, Chu KL, Xu J, et al. (2018) Characterization and Comparison of Rat Monosodium Iodoacetate and Medial Meniscal Tear Models of Osteoarthritic Pain. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
McGaraughty S, Chu KL, Xu J, et al. (2017) TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. Journal of Neurophysiology. jn.00104.2017
Jarvis MF, Scott VE, McGaraughty S, et al. (2014) A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats. Biochemical Pharmacology. 89: 536-44
Zhu CZ, Vortherms TA, Zhang M, et al. (2014) Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models. The Journal of Pain : Official Journal of the American Pain Society. 15: 387.e1-14
Xu J, Chu KL, Zhu CZ, et al. (2014) A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain. Journal of Neurophysiology. 111: 394-404
Leys LJ, Chu KL, Xu J, et al. (2013) Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats. Pain. 154: 1092-102
Xu J, Chu KL, Brederson JD, et al. (2012) Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. Journal of Neuroscience Research. 90: 1597-606
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