David Carling, Ph.D.

Affiliations: 
Clinical Sciences Centre 
Area:
Metabolic signalling
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"David Carling"
Bio:

AMPK

Mean distance: 19.24 (cluster 6)
 
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Publications

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Nguyen-Tu MS, Harris J, Martinez-Sanchez A, et al. (2022) Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase. Diabetologia
Wilson L, Pollard A, Penfold L, et al. (2021) Chronic activation of AMP-activated protein kinase leads to early onset polycystic kidney phenotype. Clinical Science (London, England : 1979)
Spengler K, Zibrova D, Woods A, et al. (2020) Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. The Biochemical Journal
Bonnard C, Navaratnam N, Ghosh K, et al. (2020) A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling. The Journal of Experimental Medicine. 217
Seneviratne A, Cave L, Hyde G, et al. (2020) Metformin directly suppresses atherosclerosis in normoglycemic mice via haematopoietic Adenosine Monophosphate-Activated Protein Kinase (AMPK). Cardiovascular Research
Seneviratne AN, Han Y, Wong E, et al. (2020) Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1 (ATF1). Circulation Research
Steinberg GR, Carling D. (2019) AMP-activated protein kinase: the current landscape for drug development. Nature Reviews. Drug Discovery
Boyle J, Seneviratne A, Han Y, et al. (2019) Vertebrate Hematoma Resolution Is Directed By Activating Transcription Factor 1 (Atf1) And Adenosine-Monophosphate-Activated-Protein-Kinase (Ampk) Atherosclerosis. 287: e246
Carling D, Penfold L, Woods A, et al. (2018) CAMKK2 promotes prostate cancer independently of AMPK via increased lipogenesis. Cancer Research
Hinchy EC, Gruszczyk AV, Willows R, et al. (2018) Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. The Journal of Biological Chemistry
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