Ashwin Unnikrishnan, Ph.D.
Affiliations: | 2000-2003 | Washington University, Saint Louis, St. Louis, MO | |
| 2004-2009 | Basic Sciences Division | Fred Hutchinson Cancer Research Center, Seattle, WA, United States | |
| 2011- | Lowy Cancer Research Centre | University of New South Wales, Kensington, New South Wales, Australia |
Area:
Molecular Biology, Biochemistry, Cell Biology, Hematopoietic CancersWebsite:
https://powcs.med.unsw.edu.au/node/301300772Google:
""Ashwin Unnikrishan" + Sydney"Bio:
I am a biomedical research scientist and Head of the Molecular Mechanisms in Leukaemia laboratory at the Lowy Cancer Research Centre, University of New South Wales.
My lab's research interests in haematological cancers and Myelodysplastic Syndrome (MDS) in particular. We use a combination of genomics, epigenomics, molecular biology and stem cell biology techniques to understand the molecular mechanisms driving leukaemia, as well as that underpinning response to therapy.
I received my Ph.D. in Molecular & Cellular Biology from the Fred Hutchinson Cancer Research Center and the University of Washington (U.S.A.) in 2009, and my A.B., Magna cum laude, in Biochemistry and Molecular Biology from Washington University in St. Louis (U.S.A.) in 2003.
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Toshio Tsukiyama | grad student | 2004-2009 | Fred Hutchinson Cancer Center | |
| (PhD Thesis: The role of histone modifications in DNA replication.) | ||||
| John Pimanda | post-doc | 2011-2018 | University of New South Wales | |
| Gary Stormo | research scientist | 2001-2001 | Washington University School of Medicine (Computational Biology Tree) | |
| (Undergraduate research) | ||||
| Eduardo A. Groisman | research scientist | 2001-2003 | Washington University School of Medicine | |
| (Undergraduate research) | ||||
| Craig S. Pikaard | research scientist | 2003-2004 | Washington University (Cell Biology Tree) | |
| (Undergraduate research) | ||||
Children
Sign in to add trainee| Mangalangi Udayakumar | research assistant | 2020- | University of New South Wales |
| Lachlin Vaughan | grad student | 2017- | University of New South Wales |
| Veena Gullapalli | grad student | 2020- | University of New South Wales |
| Yi Fang Guan | grad student | 2012-2016 | University of New South Wales |
| Govardhan Anande | grad student | 2016-2020 | University of New South Wales |
| Govardhan Anande | post-doc | 2020- | University of New South Wales |
| Nandan Deshpande | post-doc | 2020- | University of New South Wales |
| Anh Vo Ngoc | research scientist | 2016-2016 | University of New South Wales |
| Xioaming (Keith) Fu | research scientist | 2017-2017 | University of New South Wales |
| Varsha Balraj | research scientist | 2020-2020 | University of New South Wales |
Collaborators
Sign in to add collaborator| John Pimanda | collaborator | 2011- | University of New South Wales |
| Jason W.H. Wong | collaborator | 2011- | University of Hong Kong Faculty of Medicine |
| Marc R. Wilkins | collaborator | 2015- | University of New South Wales (Microtree) |
| Naresh Kumar | collaborator | 2016- | University of New South Wales |
BETA: Related publications
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Publications
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| Schnegg-Kaufmann AS, Thoms JAI, Bhuyan GS, et al. (2022) Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy. Blood |
| Saini SK, Holmberg-Thydén S, Bjerregaard AM, et al. (2022) Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies. Leukemia. 36: 2734-2738 |
| John Newton Amaldoss M, Pandzic E, Koshy P, et al. (2022) Detection and Quantification of Nanoparticle-Induced Intracellular ROS in Live Cells by Laser Scanning Confocal Microscopy. Methods (San Diego, Calif.) |
| Chandrakanthan V, Rorimpandey P, Zanini F, et al. (2022) Mesoderm-derived PDGFRA cells regulate the emergence of hematopoietic stem cells in the dorsal aorta. Nature Cell Biology |
| Liu L, Vujovic A, Deshpande NP, et al. (2022) The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors. Nature Communications. 13: 3833 |
| Amaldoss MJN, Mehmood R, Yang JL, et al. (2022) Anticancer therapeutic effect of cerium-based nanoparticles: known and unknown molecular mechanisms. Biomaterials Science |
| Liu YC, Kwon J, Fabiani E, et al. (2022) Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy. The New England Journal of Medicine. 386: 1998-2010 |
| Yang J, Gao C, Liu M, et al. (2021) Targeting an inducible SALL4-mediated cancer vulnerability with sequential therapy. Cancer Research |
| Lorenzi L, Chiu HS, Avila Cobos F, et al. (2021) Publisher Correction: The RNA Atlas expands the catalog of human non-coding RNAs. Nature Biotechnology |
| Lorenzi L, Chiu HS, Avila Cobos F, et al. (2021) The RNA Atlas expands the catalog of human non-coding RNAs. Nature Biotechnology |