Joshua Brooks, Ph.D.

Affiliations: 
Pharmacology University of California, San Diego, La Jolla, CA 
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"Joshua Brooks"
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Publications

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Musiek ES, Brooks JD, Joo M, et al. (2019) Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 294: 6657
Brooks JD, Musiek ES, Koestner TR, et al. (2011) The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation. Journal of Neurochemistry. 119: 604-16
Kleman AM, Brown JE, Zeiger SL, et al. (2010) p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone. Autophagy. 6: 948-9
Brown JE, Zeiger SL, Hettinger JC, et al. (2010) Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5242-52
Musiek ES, Brooks JD, Joo M, et al. (2008) Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 283: 19927-35
Brooks JD, Milne GL, Yin H, et al. (2008) Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid. The Journal of Biological Chemistry. 283: 12043-55
Milne GL, Yin H, Brooks JD, et al. (2007) Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. Methods in Enzymology. 433: 113-26
Dostalek M, Brooks JD, Hardy KD, et al. (2007) In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers. Molecular Pharmacology. 72: 1419-24
Yin H, Brooks JD, Gao L, et al. (2007) Identification of novel autoxidation products of the omega-3 fatty acid eicosapentaenoic acid in vitro and in vivo. The Journal of Biological Chemistry. 282: 29890-901
McLaughlin JN, Shen L, Holinstat M, et al. (2005) Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1 Journal of Biological Chemistry. 280: 25048-25059
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