Claire Townsend, Ph.D.
Affiliations: | GlaxoSmithKline, Collegeville, PA, United States |
Area:
Drug Development, ion channelsGoogle:
"Claire Townsend"Mean distance: 15.54 (cluster 6) | S | N | B | C | P |
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Publications
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| Townsend C, Brown BS. (2013) Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 10.16 |
| Gillie DJ, Novick SJ, Donovan BT, et al. (2013) Development of a high-throughput electrophysiological assay for the human ether-Ã -go-go related potassium channel hERG. Journal of Pharmacological and Toxicological Methods. 67: 33-44 |
| Gillie DJ, Novick SJ, Donovan BT, et al. (2012) Development and Validation of a high-throughput Structure-Activity Relationship Assay for the hERG Potassium Channel Biophysical Journal. 102 |
| Dale TJ, Townsend C, Hollands EC, et al. (2007) Population patch clamp electrophysiology: a breakthrough technology for ion channel screening. Molecular Biosystems. 3: 714-22 |
| Peat AJ, Townsend C, Craig McKay M, et al. (2004) 3-trifluoromethyl-4-nitro-5-arylpyrazoles are novel K(ATP) channel agonists. Bioorganic & Medicinal Chemistry Letters. 14: 813-6 |
| Peat AJ, Townsend C, Worley JF, et al. (2002) Synthesis and evaluation of 7-substituted-3-cyclobutylamino-4H-1,2,4-benzothiadiazine-1,1-dioxide derivatives as K(ATP) channel agonists. Bioorganic & Medicinal Chemistry Letters. 12: 2977-80 |
| Townsend C, Rosenberg RL. (1995) Characterization of a chloride channel reconstituted from cardiac sarcoplasmic reticulum. The Journal of Membrane Biology. 147: 121-36 |
| Wang Y, Townsend C, Rosenberg RL. (1993) Regulation of cardiac L-type Ca channels in planar lipid bilayers by G proteins and protein phosphorylation. The American Journal of Physiology. 264: C1473-9 |