James T. McLaughlin, Ph.D.

Affiliations: 
Ora Clinical Ora Clinical 
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"James McLaughlin"
Mean distance: 15.54 (cluster 6)
 
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Publications

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Loechner KJ, Patel S, Fordham L, et al. (2010) Decreased bone mineral density and vertebral compression fractures in a young adult male with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH): is CAH an unrecognized population at risk for glucocorticoid-induced osteoporosis? Journal of Pediatric Endocrinology & Metabolism : Jpem. 23: 179-87
Loechner KJ, Salmon WC, Fu J, et al. (2009) Cell Cycle-Dependent Localization of Voltage-Dependent Calcium Channels and the Mitotic Apparatus in a Neuroendocrine Cell Line(AtT-20). International Journal of Cell Biology. 2009: 487959
Barron SC, McLaughlin JT, See JA, et al. (2009) An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine. Molecular Pharmacology. 76: 253-63
McLaughlin JT, Barron SC, See JA, et al. (2009) Conformational changes in alpha 7 acetylcholine receptors underlying allosteric modulation by divalent cations. Bmc Pharmacology. 9: 1
McLaughlin JT, Fu J, Rosenberg RL. (2007) Agonist-driven conformational changes in the inner beta-sheet of alpha7 nicotinic receptors. Molecular Pharmacology. 71: 1312-8
McLaughlin JT, Fu J, Sproul AD, et al. (2006) Role of the outer beta-sheet in divalent cation modulation of alpha7 nicotinic receptors. Molecular Pharmacology. 70: 16-22
Lyford LK, Sproul AD, Eddins D, et al. (2003) Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors. Molecular Pharmacology. 64: 650-8
Eddins D, Sproul AD, Lyford LK, et al. (2002) Glutamate 172, essential for modulation of L247T alpha7 ACh receptors by Ca2+, lines the extracellular vestibule. American Journal of Physiology. Cell Physiology. 283: C1454-60
Levandoski MM, Lin Y, Moise L, et al. (1999) Chimeric analysis of a neuronal nicotinic acetylcholine receptor reveals amino acids conferring sensitivity to alpha-bungarotoxin. The Journal of Biological Chemistry. 274: 26113-9
Loechner KJ, Knox RJ, McLaughlin JT, et al. (1999) Dexamethasone-mediated inhibition of calcium transients and ACTH release in a pituitary cell line (AtT-20). Steroids. 64: 404-12
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