Ann M. Szczepanik, Ph.D.

Affiliations: 
2001 Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Neuroscience Biology, Pathology
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"Ann Szczepanik"
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Garth E. Ringheim grad student 2001 Rutgers, New Brunswick
 (Microglia mediate an immune response; to beta-amyloid peptides: Implications for the pathogenesis of Alzheimer's disease.)
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Publications

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Szczepanik AM, Rampe D, Ringheim GE. (2008) Amyloid-β peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo: Amyloid-β peptides induce cytokines Journal of Neurochemistry. 77: 304-317
Ringheim GE, Szczepanik AM. (2006) Brain inflammation, cholesterol, and glutamate as interconnected participants in the pathology of Alzheimer's disease. Current Pharmaceutical Design. 12: 719-38
Szczepanik AM, Wordliczek J, Serednicki W, et al. (2004) Pentoxifylline does not affect nociception if administered postoperatively. Polish Journal of Pharmacology. 56: 611-6
Szczepanik AM, Ringheim GE. (2003) IL-10 and glucocorticoids inhibit Abeta(1-42)- and lipopolysaccharide-induced pro-inflammatory cytokine and chemokine induction in the central nervous system. Journal of Alzheimer's Disease : Jad. 5: 105-17
Szczepanik AM, Rampe D, Ringheim GE. (2001) Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. Journal of Neurochemistry. 77: 304-17
Szczepanik AM, Funes S, Petko W, et al. (2001) IL-4, IL-10 and IL-13 modulate A beta(1--42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line. Journal of Neuroimmunology. 113: 49-62
Ringheim GE, Szczepanik AM, Petko W, et al. (1998) Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex. Brain Research. Molecular Brain Research. 55: 35-44
Szczepanik A, Petko W, Ringheim G. (1998) Synergistic induction of TNF-α expression by αβ (1–42) and IFN-γ in microglial cells is inhibited by IL-4, IL-10 and IL-13 Journal of Neuroimmunology. 90: 53
Ringheim GE, Petko W, Burgher K, et al. (1997) Enhancement of beta-amyloid precursor protein transcription by the soluble interleukin-6 receptor/interleukin-6 complex Faseb Journal. 11
Pan J, Burgher KL, Szczepanik AM, et al. (1996) Tyrosine phosphorylation of inducible nitric oxide synthase: implications for potential post-translational regulation. The Biochemical Journal. 314: 889-94
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