Shi-Fang Lu, Ph.D.

Affiliations: 
2000 Lehigh University, Bethlehem, PA, United States 
Area:
Cell Biology, Neuroscience Biology, Molecular Biology
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"Shi-Fang Lu"
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Parents

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Neal G. Simon grad student 2000 Lehigh University
 (Autoregulation of androgen receptor by androgen in mouse brain: Characterizing the mechanism of androgen action.)
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Publications

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Lee RJ, Coccaro EF, Cremers H, et al. (2013) A novel V1a receptor antagonist blocks vasopressin-induced changes in the CNS response to emotional stimuli: an fMRI study. Frontiers in Systems Neuroscience. 7: 100
Fabio KM, Guillon CD, Lu SF, et al. (2013) Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist. Journal of Pharmaceutical Sciences. 102: 2033-43
Fabio K, Guillon C, Lacey CJ, et al. (2012) Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging. Bioorganic & Medicinal Chemistry. 20: 1337-45
Simon NG, Guillon C, Fabio K, et al. (2008) Vasopressin antagonists as anxiolytics and antidepressants: recent developments. Recent Patents On Cns Drug Discovery. 3: 77-93
Guillon CD, Koppel GA, Brownstein MJ, et al. (2007) Azetidinones as vasopressin V1a antagonists. Bioorganic & Medicinal Chemistry. 15: 2054-80
Simon NG, Mo Q, Hu S, et al. (2006) Hormonal pathways regulating intermale and interfemale aggression. International Review of Neurobiology. 73: 99-123
Mo Q, Lu SF, Simon NG. (2006) Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity. The Journal of Steroid Biochemistry and Molecular Biology. 99: 50-8
Ferris CF, Lu SF, Messenger T, et al. (2006) Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior. Pharmacology, Biochemistry, and Behavior. 83: 169-74
Hu S, Lu SF, Kaplan JR, et al. (2005) ERbeta protein expression in female cynomolgus monkey and CF-1 mouse brain: Western analysis. Journal of Neurobiology. 64: 298-309
Mo Q, Lu SF, Hu S, et al. (2004) DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity. Brain Research. Molecular Brain Research. 126: 165-72
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