Akhil Bhalla, Ph.D.
Affiliations: | Proteostasis Therapeutics, Inc. |
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"Akhil Bhalla"Mean distance: 15.95 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Edwin R. Chapman | grad student | 2001-2006 | UW Madison | |
| (The role of synaptotagmin in SNARE-catalyzed membrane fusion.) | ||||
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Publications
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| Bhalla A, Vetanovetz CP, Morel E, et al. (2012) The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. Neurobiology of Disease. 47: 126-34 |
| Abdulreda MH, Bhalla A, Rico F, et al. (2009) Pulling force generated by interacting SNAREs facilitates membrane hemifusion. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 301-10 |
| Zhang Z, Bhalla A, Dean C, et al. (2009) Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals. Nature Neuroscience. 12: 163-71 |
| Bhalla A, Chicka MC, Chapman ER. (2008) Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoforms. The Journal of Biological Chemistry. 283: 21799-807 |
| Abdulreda MH, Bhalla A, Chapman ER, et al. (2008) Atomic force microscope spectroscopy reveals a hemifusion intermediate during soluble N-ethylmaleimide-sensitive factor-attachment protein receptors-mediated membrane fusion. Biophysical Journal. 94: 648-55 |
| Bhalla A, Chicka MC, Tucker WC, et al. (2006) Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion. Nature Structural & Molecular Biology. 13: 323-30 |
| Wang P, Chicka MC, Bhalla A, et al. (2005) Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor. Molecular and Cellular Biology. 25: 8693-702 |
| Bhalla A, Tucker WC, Chapman ER. (2005) Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion. Molecular Biology of the Cell. 16: 4755-64 |
| Liu T, Tucker WC, Bhalla A, et al. (2005) SNARE-driven, 25-millisecond vesicle fusion in vitro. Biophysical Journal. 89: 2458-72 |
| Madziva MT, Bai J, Bhalla A, et al. (2005) Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor. British Journal of Pharmacology. 144: 761-71 |