Leroy F. Liu

Affiliations: 
1980-1992 Biological Chemistry Johns Hopkins University, Baltimore, MD 
 1992-2014 Pharmacology Rutgers University, New Brunswick/Piscataway, New Brunswick, NJ, United States 
 2014- Cancer Biology and Therapeutics Taipei Medical University 
Area:
Biochemistry, Pharmacology, Molecular Biology
Website:
https://tmu.pure.elsevier.com/en/persons/leroy-fong-liu
Google:
"Leroy Fong Liu" OR "Leroy F. Liu"
Bio:

https://orcid.org/0000-0001-9396-763X
https://books.google.com/books?id=sFRRAQAAMAAJ

Mean distance: (not calculated yet)
 

Parents

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James C. Wang grad student 1977 UC Berkeley
 (Interactions Between E. Coli ω Protein and Deoxyribonucleic Acid)
Bruce Alberts post-doc 1978-1980 UCSF

Children

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Xin Bi grad student 1995 Johns Hopkins
Sai-Peng Sim grad student 2001 Rutgers, New Brunswick
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Publications

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Ban Y, Ho CW, Lin RK, et al. (2013) Activation of a novel ubiquitin-independent proteasome pathway when RNA polymerase II encounters a protein roadblock. Molecular and Cellular Biology. 33: 4008-16
Azarova AM, Lin RK, Tsai YC, et al. (2010) Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia. Biochemical and Biophysical Research Communications. 399: 66-71
Rzuczek SG, Pilch DS, Liu A, et al. (2010) Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents. Journal of Medicinal Chemistry. 53: 3632-44
Lin CP, Ban Y, Lyu YL, et al. (2009) Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks. The Journal of Biological Chemistry. 284: 28084-92
Lin CP, Ban Y, Lyu YL, et al. (2008) A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes. The Journal of Biological Chemistry. 283: 21074-83
Satyanarayana M, Rzuczek SG, Lavoie EJ, et al. (2008) Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency. Bioorganic & Medicinal Chemistry Letters. 18: 3802-4
Fu X, Wan S, Lyu YL, et al. (2008) Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. Plos One. 3: e2009
Lyu YL, Kerrigan JE, Lin CP, et al. (2007) Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane. Cancer Research. 67: 8839-46
Azarova AM, Lyu YL, Lin CP, et al. (2007) Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies. Proceedings of the National Academy of Sciences of the United States of America. 104: 11014-9
Hars ES, Lyu YL, Lin CP, et al. (2006) Role of apoptotic nuclease caspase-activated DNase in etoposide-induced treatment-related acute myelogenous leukemia. Cancer Research. 66: 8975-9
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