Grant A. Krafft
Affiliations: | Northwestern University, Evanston, IL |
Area:
Neuroscience BiologyGoogle:
"Grant Krafft"Mean distance: 53433
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Publications
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| Krafft GA, Jerecic J, Siemers E, et al. (2022) ACU193: An Immunotherapeutic Poised to Test the Amyloid β Oligomer Hypothesis of Alzheimer's Disease. Frontiers in Neuroscience. 16: 848215 |
| Wang X, Kastanenka KV, Arbel-Ornath M, et al. (2018) An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging. Scientific Reports. 8: 4634 |
| Goure WF, Krafft GA, Jerecic J, et al. (2014) Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics. Alzheimer's Research & Therapy. 6: 42 |
| Hefti F, Goure WF, Jerecic J, et al. (2013) The case for soluble Aβ oligomers as a drug target in Alzheimer's disease. Trends in Pharmacological Sciences. 34: 261-6 |
| Krafft G, Hefti F, Goure W, et al. (2013) O2-06-03: ACU-193: A candidate therapeutic antibody that selectively targets soluble beta-amyloid oligomers Alzheimer's & Dementia. 9: P326-P326 |
| Krafft GA, Klein WL. (2010) ADDLs and the signaling web that leads to Alzheimer's disease. Neuropharmacology. 59: 230-42 |
| Gandy S, Simon AJ, Steele JW, et al. (2010) Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Annals of Neurology. 68: 220-30 |
| Zhao WQ, Lacor PN, Chen H, et al. (2009) Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. The Journal of Biological Chemistry. 284: 18742-53 |
| Zhao WQ, De Felice FG, Fernandez S, et al. (2008) Amyloid beta oligomers induce impairment of neuronal insulin receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 246-60 |
| Look GC, Jerecic J, Cherbavaz DB, et al. (2007) Discovery of ADDL--targeting small molecule drugs for Alzheimer's disease. Current Alzheimer Research. 4: 562-7 |