Yi-Chun Hsiao, PhD

Affiliations: 
Genentech, Inc., San Francisco, CA, United States 
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"Yi-Chun Hsiao"
Mean distance: 16.56 (cluster 46)
 
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Russell J. Ferland grad student 2011 RPI
 (AHI1, a ciliopathy-causing gene, is involved in the formation and function of primary cilia through the regulation of intracellular vesicular trafficking.)
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Publications

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Hsiao YC, Muñoz-Estrada J, Tuz K, et al. (2021) The transition zone protein AHI1 regulates neuronal ciliary trafficking of MCHR1 and its downstream signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Heger K, Wickliffe KE, Ndoja A, et al. (2018) OTULIN limits cell death and inflammation by deubiquitinating LUBAC. Nature
Huang CS, Oberbeck N, Hsiao YC, et al. (2018) Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure (London, England : 1993)
Tuz K, Hsiao YC, Juárez O, et al. (2013) The Joubert syndrome-associated missense mutation (V443D) in the Abelson-helper integration site 1 (AHI1) protein alters its localization and protein-protein interactions. The Journal of Biological Chemistry. 288: 13676-94
Hsiao YC, Tuz K, Ferland RJ. (2012) Trafficking in and to the primary cilium. Cilia. 1: 4
Westfall JE, Hoyt C, Liu Q, et al. (2010) Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8759-68
Hsiao YC, Tong ZJ, Westfall JE, et al. (2009) Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking. Human Molecular Genetics. 18: 3926-41
Ferland RJ, Batiz LF, Neal J, et al. (2009) Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia. Human Molecular Genetics. 18: 497-516
Doering JE, Kane K, Hsiao YC, et al. (2008) Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies. The Journal of Comparative Neurology. 511: 238-56
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