H Uri Saragovi

McGill University, Montreal, QC, Canada 
Pharmacology, Neuroscience Biology, Cell Biology
"H Saragovi"
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Barcelona PF, Sitaras N, Galan A, et al. (2016) p75NTR and Its Ligand ProNGF Activate Paracrine Mechanisms Etiological to the Vascular, Inflammatory, and Neurodegenerative Pathologies of Diabetic Retinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8826-41
Tong W, Maira M, Gagnon M, et al. (2015) Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology. Plos One. 10: e0134255
Barcelona PF, Saragovi HU. (2015) A Pro-Nerve Growth Factor (proNGF) and NGF Binding Protein, α2-Macroglobulin, Differentially Regulates p75 and TrkA Receptors and Is Relevant to Neurodegeneration Ex Vivo and In Vivo. Molecular and Cellular Biology. 35: 3396-408
Goupil E, Fillion D, Clément S, et al. (2015) Angiotensin II type I and prostaglandin F2α receptors cooperatively modulate signaling in vascular smooth muscle cells. The Journal of Biological Chemistry. 290: 3137-48
Galan A, Dergham P, Escoll P, et al. (2014) Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells. Plos One. 9: e101349
Brahimi F, Ko E, Malakhov A, et al. (2014) Combinatorial assembly of small molecules into bivalent antagonists of TrkC or TrkA receptors Plos One. 9
Mysona BA, Al-Gayyar MM, Matragoon S, et al. (2013) Modulation of p75(NTR) prevents diabetes- and proNGF-induced retinal inflammation and blood-retina barrier breakdown in mice and rats. Diabetologia. 56: 2329-39
Garcia AG, Nedev H, Bijian K, et al. (2013) Reduced in vivo lung metastasis of a breast cancer cell line after treatment with Herceptin mAb conjugated to chemotherapeutic drugs. Oncogene. 32: 2527-33
Ivanisevic L, Saragovi HU. (2013) Neurotrophins Handbook of Biologically Active Peptides. 1639-1646
Ettinger K, Lecht S, Arien-Zakay H, et al. (2012) Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model. Cellular Signalling. 24: 2378-88
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