H Uri Saragovi

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Pharmacology, Neuroscience Biology, Cell Biology
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"H Saragovi"
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Publications

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Galan A, Papaluca A, Nejatie A, et al. (2023) GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancer. Frontiers in Oncology. 13: 1134763
Brahimi F, Galan A, Siegel S, et al. (2021) . Molecular Pharmacology
Brahimi F, Galan A, Jmaeff S, et al. (2020) Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands. Iscience. 23: 101447
Mossa AH, Galan A, Cammisotto PG, et al. (2020) Antagonism of proNGF or its receptor p75 reverses remodelling and improves bladder function in a mouse model of diabetic voiding dysfunction. Diabetologia
Jmaeff S, Sidorova Y, Lippiatt H, et al. (2020) Small-molecule ligands that bind the RET receptor activate neuroprotective signals independent of but modulated by co-receptor GFRα1. Molecular Pharmacology
Jmaeff S, Sidorova Y, Nedev H, et al. (2020) Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors. The Journal of Biological Chemistry. 295: 6532-6542
Szobota S, Mathur PD, Siegel S, et al. (2019) BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss. Plos One. 14: e0224022
Saragovi HU, Galan A, Levin LA. (2019) Neuroprotection: Pro-survival and Anti-neurotoxic Mechanisms as Therapeutic Strategies in Neurodegeneration. Frontiers in Cellular Neuroscience. 13: 231
Tong W, Maira M, Roychoudhury R, et al. (2019) Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy. Cell Chemical Biology
Galán A, Jmaeff S, Barcelona PF, et al. (2017) In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death. Cell Death & Disease. 8: 3222
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