Mufida B. El-Ghundi, Ph.D.

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Neuroscience Biology
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"Mufida El-Ghundi"
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Susan R. George grad student 2001 University of Toronto
 (Insights into the role of the dopamine D1 receptor in brain function: Studies using a gene deletion model.)
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Publications

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El-Ghundi MB, Fan T, Karasinska JM, et al. (2010) Restoration of amphetamine-induced locomotor sensitization in dopamine D1 receptor-deficient mice. Psychopharmacology. 207: 599-618
El-Ghundi M, O'Dowd BF, George SR. (2007) Insights into the role of dopamine receptor systems in learning and memory. Reviews in the Neurosciences. 18: 37-66
Rashid AJ, So CH, Kong MM, et al. (2007) D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 104: 654-9
Seeman P, Weinshenker D, Quirion R, et al. (2005) Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8
El-Ghundi M, O'Dowd BF, Erclik M, et al. (2003) Attenuation of sucrose reinforcement in dopamine D1 receptor deficient mice. The European Journal of Neuroscience. 17: 851-62
El-Ghundi M, O'Dowd BF, George SR. (2001) Prolonged fear responses in mice lacking dopamine D1 receptor. Brain Research. 892: 86-93
Karasinska JM, George SR, El-Ghundi M, et al. (2000) Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors. European Journal of Pharmacology. 399: 171-81
El-Ghundi M, Fletcher PJ, Drago J, et al. (1999) Spatial learning deficit in dopamine D(1) receptor knockout mice. European Journal of Pharmacology. 383: 95-106
El-Ghundi M, George SR, Drago J, et al. (1998) Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. European Journal of Pharmacology. 353: 149-58
el-Ghundi M, Kalant H, Lê AD, et al. (1989) The contribution of environmental cues to cross-tolerance between ethanol and pentobarbital. Psychopharmacology. 97: 194-201
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