James S. Sutcliffe

Vanderbilt University, Nashville, TN 
Genetics, Neuroscience Biology, Molecular Biology, Pathology
"James Sutcliffe"
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Sanders SJ, He X, Willsey AJ, et al. (2015) Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci. Neuron. 87: 1215-1233
Cartier E, Hamilton PJ, Belovich AN, et al. (2015) Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors. Ebiomedicine. 2: 135-146
Hamilton PJ, Shekar A, Belovich AN, et al. (2015) Zn(2+) reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder. Molecular Autism. 6: 8
Mazalouskas M, Jessen T, Varney S, et al. (2015) Integrin β3 Haploinsufficiency Modulates Serotonin Transport and Antidepressant-Sensitive Behavior in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2015-24
Chen R, Wei Q, Zhan X, et al. (2015) A haplotype-based framework for group-wise transmission/disequilibrium tests for rare variant association analysis. Bioinformatics (Oxford, England). 31: 1452-9
Chaste P, Klei L, Sanders SJ, et al. (2015) A genome-wide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity? Biological Psychiatry. 77: 775-84
Trubetskoy V, Rodriguez A, Dave U, et al. (2015) Consensus Genotyper for Exome Sequencing (CGES): improving the quality of exome variant genotypes. Bioinformatics (Oxford, England). 31: 187-93
Buxbaum JD, Bolshakova N, Brownfeld JM, et al. (2014) The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses. Molecular Autism. 5: 34
Samocha KE, Robinson EB, Sanders SJ, et al. (2014) A framework for the interpretation of de novo mutation in human disease. Nature Genetics. 46: 944-50
Chaste P, Sanders SJ, Mohan KN, et al. (2014) Modest impact on risk for autism spectrum disorder of rare copy number variants at 15q11.2, specifically breakpoints 1 to 2. Autism Research : Official Journal of the International Society For Autism Research. 7: 355-62
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