Trevor M. Lewis

Affiliations: 
The University of New South Wales, Australia 
Area:
Ligand gated ion channels, glycine receptors
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"Trevor Lewis"
Mean distance: 15.22 (cluster 11)
 
SNBCP

Parents

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David Colquhoun post-doc 1994-1997 UCL
Peter R. Schofield post-doc 1997-2003 Garvan Institute

Collaborators

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Lucia Sivilotti collaborator 1994-1997 UCL
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Publications

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Indurthi DC, Qudah T, Liao VW, et al. (2018) Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry. Pharmacological Research
Indurthi DC, Lewis TM, Ahring PK, et al. (2016) Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State. Plos One. 11: e0161154
Carland JE, Yamamoto I, Hanrahan JR, et al. (2015) A hydrophobic area of the GABA ρ₁ receptor containing phenylalanine 124 influences both receptor activation and deactivation. Journal of Molecular Neuroscience : Mn. 55: 305-13
Absalom NL, Quek G, Lewis TM, et al. (2013) Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed. The Journal of Biological Chemistry. 288: 26521-32
Barry PH, Lewis TM, Moorhouse AJ. (2013) An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology. European Biophysics Journal : Ebj. 42: 631-46
Huang SH, Lewis TM, Lummis SC, et al. (2012) Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptors. Neuropharmacology. 63: 1127-39
Cederholm JM, Absalom NL, Sugiharto S, et al. (2010) Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor. Journal of Neurochemistry. 115: 1245-55
Sugiharto S, Carland JE, Lewis TM, et al. (2010) External divalent cations increase anion-cation permeability ratio in glycine receptor channels. PflüGers Archiv : European Journal of Physiology. 460: 131-52
Barry PH, Sugiharto S, Lewis TM, et al. (2010) Further analysis of counterion permeation through anion-selective glycine receptor channels. Channels (Austin, Tex.). 4: 142-9
Cederholm JM, Schofield PR, Lewis TM. (2009) Gating mechanisms in Cys-loop receptors. European Biophysics Journal : Ebj. 39: 37-49
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