Nicholas Douris, Ph.D.

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
Animal Physiology Biology
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Carla B. Green grad student 2009 UVA
 (Nocturnin, a circadian deadenylase, alters lipid absorption and confers resistance to diet-induced obesity and hepatic steatosis.)
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Publications

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Singhal G, Douris N, Fish AJ, et al. (2016) Fibroblast growth factor 21 has no direct role in regulating fertility in female mice Molecular Metabolism
Douris N, Melman T, Pecherer JM, et al. (2015) Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet. Biochimica Et Biophysica Acta. 1852: 2056-65
Chee MJ, Douris N, Forrow AB, et al. (2015) Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 1808-16
Carracedo A, Rousseau D, Douris N, et al. (2015) The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis. International Journal of Biological Sciences. 11: 629-32
Douris N, Maratos-Flier E. (2013) Two paths diverge in the brain: melanin-concentrating hormone controls hepatic and adipose metabolism. Gastroenterology. 144: 501-4
Fisher FM, Kleiner S, Douris N, et al. (2012) FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes & Development. 26: 271-81
Douris N, Kojima S, Pan X, et al. (2011) Nocturnin regulates circadian trafficking of dietary lipid in intestinal enterocytes. Current Biology : Cb. 21: 1347-55
Gilbert MR, Douris N, Tongjai S, et al. (2011) Nocturnin expression is induced by fasting in the white adipose tissue of restricted fed mice. Plos One. 6: e17051
Kawai M, Green CB, Lecka-Czernik B, et al. (2010) A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation. Proceedings of the National Academy of Sciences of the United States of America. 107: 10508-13
Douris N, Green CB. (2008) NOC out the fat: a short review of the circadian deadenylase Nocturnin. Annals of Medicine. 40: 622-6
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