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Andrew Metha, BSc, BSc(Optom), PGCertOcTher, PhD

Affiliations: 
Optometry & Vision Sciences University of Melbourne, Parkville, Victoria, Australia 
Area:
Vision, Adaptive Optics, Physiological Optics, Color Vision, Neurophysiology, Retina
Website:
http://www.optometry.unimelb.edu.au/research/methaLab.html
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"Andrew Metha - Google Scholar"
Bio:

Andrew Metha is currently an Associate Professor in the Department of Optometry and Vision Sciences at the University of Melbourne, where he has taught at all levels in the Bachelor and now new Postgraduate Optometry Degree courses.

His first degree was a Bachelor of Science (Physics and Mathematics) from Monash University, before undertaking his Optometry undergraduate degree from the University of Melbourne where he also obtained his PhD. Andrew currently holds a therapeutically endorsed optometry registration in Australia, and maintains clinical practice though the University optometry training clinics. He is an eclectic vision scientist, first gaining expertise in psychophysical methods of understanding visual processes during his PhD, then branching into single and multi-cell electrophysiological recordings in the visual cortex to investigate adaptation and brain plasticity, and most recently uses adaptive optics to directly image single cells and other microstructure in living eyes. He joined the University of Melbourne department in 2000 after serving postdoctoral positions in Montreal (McGill Vision Research Unit), the University of Rochester's Centre for Visual Science and the Psychobiology Laboratory in Canberra's Australian National University.

With this diverse range of exposure and experience, Andrew brings a multi-disciplinary approach to bear on the question of how we see.

Andrew's laboratories (in the Alice Hoy Building and the Melbourne Brain Centre) use adaptive optics technologies to image cellular structure and function in the living retina. The broad research aims are to understand the fundamental workings of the living retina on the microscopic scale. Of particular interest is how this becomes compromised in sight-debilitating diseases such as diabetes and glaucoma, and whether we can see early evidence in the eye for other neurological/brain conditions. The labs combine a range of investigative tools including high-resolution non-invasive imaging, psychophysics, computational modeling and electrophysiology.

Current research projects make use of high speed, multi-spectral adaptive optics to visualize the smallest neurons, glial cells and blood vessels in living eyes of humans and animals. Under investigations are: the dynamics of flow and oxygen exchange at the level of individual red blood cells; the cascade of optical and physiological events that occur when a photoreceptor interacts with light; and ways to advance retinal imaging in general, exploiting the eye as a window to the brain. View Andrew's laboratory web page at: http://www.optometry.unimelb.edu.au/research/methaLab.html


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Mean distance: 13.93 (cluster 23)
 
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Parents

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David R. Badcock grad student 1990-1994 University of Melbourne
Algis Jonas Vingrys grad student 1990-1994 University of Melbourne
 (Detection and direction discrimination in terms of post-receptoral mechanisms)
Kathy T. Mullen post-doc 1994-1996 McGill Vision Research
Peter Lennie post-doc 1996-1998 Rochester
Michael B. Calford post-doc 1998-2000 ANU
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Publications

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Bedggood P, Ding Y, Metha A. (2024) Changes to the shape, orientation and packing of red cells as a function of retinal capillary size. Biomedical Optics Express. 15: 558-578
Neriyanuri S, Bedggood P, Symons RCA, et al. (2024) Validation of an automated method for studying retinal capillary blood flow. Biomedical Optics Express. 15: 802-817
Neriyanuri S, Bedggood P, Symons RCA, et al. (2023) Mapping the human parafoveal vascular network to understand flow variability in capillaries. Plos One. 18: e0292962
Britten-Jones AC, Thai L, Flanagan JPM, et al. (2023) Adaptive optics imaging in inherited retinal diseases: A scoping review of the clinical literature. Survey of Ophthalmology
Fricke TR, Metha AB, Anderson DP, et al. (2023) Does vision therapy for visual information processing improve academic performance? A randomised clinical trial. Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
Neriyanuri S, Bedggood P, Symons RCA, et al. (2023) Flow Heterogeneity and Factors Contributing to the Variability in Retinal Capillary Blood Flow. Investigative Ophthalmology & Visual Science. 64: 15
Bedggood P, Ding Y, Metha A. (2023) Measuring red blood cell shape in the human retina. Optics Letters. 48: 1554-1557
Heriot WJ, Metha AB, He Z, et al. (2022) Optimizing Retinal Thermofusion in Retinal Detachment Repair: Achieving Instant Adhesion without Air Tamponade. Ophthalmology Science. 2: 100179
Bedggood P, Britten-Jones AC, Ayton LN, et al. (2022) Assessment of photoreceptor function with ultrafast retinal densitometry. Biomedical Optics Express. 13: 5311-5326
Heriot W, Wong VH, He Z, et al. (2022) Effect of hydroxychloroquine or chloroquine and short wavelength light on retinal function and structure in mouse eyes. Clinical & Experimental Optometry. 1-9
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