Patricia M. White, Ph.D.

Affiliations: 
2010- University of Rochester University of Rochester, Rochester, NY 
Area:
Cochlea Regeneration, Noise Damage, Hearing, Development, Neurobiology
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Parents

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Ellen V. Rothenberg research assistant 1989-1991 Caltech (Cell Biology Tree)
David J. Anderson grad student 1993-2000 Caltech
 (Cellular and molecular mechanisms in autonomic neuronal differentiation.)
Andy Groves post-doc 2000-2008 House Ear Institute
Neil Segil post-doc 2000-2008 House Ear Institute, Los Angeles (Cell Biology Tree)
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Publications

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Piekna-Przybylska D, Na D, Zhang J, et al. (2024) Corrigendum: Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation. Frontiers in Cellular Neuroscience. 18: 1428589
Na D, Zhang J, Beaulac HJ, et al. (2023) Corrigendum: Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis. Frontiers in Neuroscience. 17: 1250244
Na D, Zhang J, Beaulac HJ, et al. (2023) Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis. Frontiers in Neuroscience. 17: 1106570
Piekna-Przybylska D, Na D, Zhang J, et al. (2023) Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation. Frontiers in Cellular Neuroscience. 16: 1096872
Gilels FA, Wang J, Bullen A, et al. (2022) Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss. Cell Death & Disease. 13: 971
Kwan KY, White PM. (2021) Understanding the differentiation and epigenetics of cochlear sensory progenitors in pursuit of regeneration. Current Opinion in Otolaryngology & Head and Neck Surgery
Beaulac HJ, Gilels F, Zhang J, et al. (2021) Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice. Cell Death & Disease. 12: 682
White PM. (2020) Perspectives on Human Hearing Loss, Cochlear Regeneration, and the Potential for Hearing Restoration Therapies. Brain Sciences. 10
Patel S, Shah L, Dang N, et al. (2020) SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure. Plos One. 15: e0235491
Zhang J, Wang Q, Abdul-Aziz D, et al. (2018) ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea. The European Journal of Neuroscience
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