Ralph M. Steinman, M.D.
Affiliations: | Rockefeller University, New York, NY, United States |
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2011/steinman-bio.htmlGoogle:
"Ralph Steinman"Bio:
(1943 - 2011)
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity
and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity
.
http://www.nasonline.org/member-directory/deceased-members/3012618.html
http://www.aai.org/about/History/Notable_Members/Nobel/Steinman_Ralph.html
http://en.wikipedia.org/wiki/Ralph_M._Steinman
Cross-listing: ImmunoTree
Parents
Sign in to add mentor| Elizabeth D. Hay | grad student | 1968 | Harvard Medical School (Cell Biology Tree) | |
| (M.D.) | ||||
| Zanvil A. Cohn | post-doc | 1970-1972 | Rockefeller (Cell Biology Tree) | |
| René Dubos | post-doc | 1970-1972 | Rockefeller | |
| James G. Hirsch | post-doc | 1970-1972 | Rockefeller | |
Children
Sign in to add trainee| Jeremy Luban | research assistant | Rockefeller (Microtree) | |
| Gwendalyn Randolph | grad student | (Cell Biology Tree) | |
| Wesley C. Van Voorhis | grad student | Rockerfeller University (Microtree) | |
| Davorka Messmer | grad student | 2000 | Rockefeller |
| Dennis J. Sawchuk | grad student | 2002 | Rockefeller |
| Ira Mellman | post-doc | Rockefeller (Cell Biology Tree) |
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Publications
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| Zaidi N, Quezada SA, Kuroiwa JMY, et al. (2019) Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4 effector T cell infiltration into murine pancreatic tumors. Annals of the New York Academy of Sciences |
| Randolph GJ, Beaulieu S, Lebecque S, et al. (2017) Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483. Journal of Immunology (Baltimore, Md. : 1950). 198: 4191-4194 |
| Ngu LN, Nji NN, Ambada GE, et al. (2017) In vivo targeting of protein antigens to dendritic cells using anti-DEC-205 single chain antibody improves HIV Gag specific CD4(+) T cell responses protecting from airway challenge with recombinant vaccinia-gag virus. Immunity, Inflammation and Disease |
| Sela U, Park CG, Park A, et al. (2016) Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses. Plos One. 11: e0146412 |
| Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, et al. (2015) ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis. Plos One. 10: e0124828 |
| Anandasabapathy N, Feder R, Mollah S, et al. (2014) Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of Experimental Medicine. 211: 1875-91 |
| Flacher V, Tripp CH, Mairhofer DG, et al. (2014) Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. Embo Molecular Medicine. 6: 1191-204 |
| Pantel A, Teixeira A, Haddad E, et al. (2014) Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. Plos Biology. 12: e1001759 |
| Mollah SA, Dobrin JS, Feder RE, et al. (2014) Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. The Journal of Investigative Dermatology. 134: 1265-75 |
| Mollah SA, Dobrin JS, Feder RE, et al. (2014) Correction to: “Flt3L Dependence Helps Define an Uncharacterized Subset of Murine Cutaneous Dendritic Cells” Journal of Investigative Dermatology. 134: 2850-2851 |