Bryan T. MacDonald, Ph.D.
Affiliations: | 2004 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Genetics, Animal Physiology Biology, Molecular BiologyGoogle:
"Bryan MacDonald"Mean distance: 26716.5
Parents
Sign in to add mentor| Miriam H. Meisler | grad student | 2004 | University of Michigan | |
| (Phenotype to genotype: Genetic variants of SCN1A and Dkk1.) | ||||
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Publications
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| Zhang X, MacDonald BT, Gao H, et al. (2015) Characterization of Tiki, a new family of WNT-specific metalloproteases. The Journal of Biological Chemistry |
| Niziolek PJ, MacDonald BT, Kedlaya R, et al. (2015) High-bone-mass causing mutant LRP5 receptors are resistant to endogenous inhibitors in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
| MacDonald BT, Hien A, Zhang X, et al. (2014) Disulfide bond requirements for active Wnt ligands. The Journal of Biological Chemistry. 289: 18122-36 |
| Wang L, Shalek AK, Lawrence M, et al. (2014) Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. Blood. 124: 1089-98 |
| Guo C, Sun Y, Guo C, et al. (2014) Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Developmental Biology. 385: 41-51 |
| Macaulay IC, Thon JN, Tijssen MR, et al. (2013) Canonical Wnt signaling in megakaryocytes regulates proplatelet formation. Blood. 121: 188-96 |
| Zhang X, Abreu JG, Yokota C, et al. (2012) Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 149: 1565-77 |
| Chen S, Bubeck D, MacDonald BT, et al. (2011) Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Developmental Cell. 21: 848-61 |
| MacDonald BT, Semenov MV, Huang H, et al. (2011) Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6. Plos One. 6: e23537 |
| Cui Y, Niziolek PJ, MacDonald BT, et al. (2011) Lrp5 functions in bone to regulate bone mass. Nature Medicine. 17: 684-91 |