Marina Spanos, Ph.D.

Affiliations: 
Chemistry North Carolina State University, Raleigh, NC 
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"Marina Spanos"
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SNBCP
Cross-listing: Chemistry Tree

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Clyde W. Hodge grad student 2006-2010 UNC Chapel Hill
 (Alcohol exposure leads to differential neuroadaptations in the ERK/MAPK signaling pathway in adolescents as compared to adults.)
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Publications

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Agoglia AE, Holstein SE, Small AT, et al. (2017) Comparison of the adolescent and adult mouse prefrontal cortex proteome. Plos One. 12: e0178391
Salling MC, Faccidomo SP, Li C, et al. (2014) Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol. Biological Psychiatry
Spanos M, Gras-Najjar J, Letchworth JM, et al. (2013) Quantitation of hydrogen peroxide fluctuations and their modulation of dopamine dynamics in the rat dorsal striatum using fast-scan cyclic voltammetry. Acs Chemical Neuroscience. 4: 782-9
Spanos M, Besheer J, Hodge CW. (2012) Increased sensitivity to alcohol induced changes in ERK Map kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice. Behavioural Brain Research. 230: 158-66
Holstein SE, Spanos M, Hodge CW. (2011) Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking. Alcoholism, Clinical and Experimental Research. 35: 1842-51
Lowery EG, Spanos M, Navarro M, et al. (2010) CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1241-52
Besheer J, Grondin JJ, Salling MC, et al. (2009) Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9582-91
Schroeder JP, Spanos M, Stevenson JR, et al. (2008) Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP. Neuropharmacology. 55: 546-54
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