Marina Spanos, Ph.D.

Affiliations: 
Chemistry North Carolina State University, Raleigh, NC 
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"Marina Spanos"
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SNBCP
Cross-listing: Chemistry Tree

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Clyde W. Hodge grad student 2006-2010 UNC Chapel Hill
 (Alcohol exposure leads to differential neuroadaptations in the ERK/MAPK signaling pathway in adolescents as compared to adults.)
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Publications

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Agoglia AE, Holstein SE, Small AT, et al. (2017) Comparison of the adolescent and adult mouse prefrontal cortex proteome. Plos One. 12: e0178391
Salling MC, Faccidomo SP, Li C, et al. (2014) Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol. Biological Psychiatry
Spanos M, Besheer J, Hodge CW. (2012) Increased sensitivity to alcohol induced changes in ERK Map kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice. Behavioural Brain Research. 230: 158-66
Holstein SE, Spanos M, Hodge CW. (2011) Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking. Alcoholism, Clinical and Experimental Research. 35: 1842-51
Lowery EG, Spanos M, Navarro M, et al. (2010) CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1241-52
Besheer J, Grondin JJ, Salling MC, et al. (2009) Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9582-91
Schroeder JP, Spanos M, Stevenson JR, et al. (2008) Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP. Neuropharmacology. 55: 546-54
Geroyiannaki M, Komaitis ME, Stavrakas DE, et al. (2007) Evaluation of acetaldehyde and methanol in greek traditional alcoholic beverages from varietal fermented grape pomaces (Vitis vinifera L.) Food Control. 18: 988-995
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