Meir H. Scheinfeld, Ph.D.

Affiliations: 
2005 Yeshiva University, New York, NY, United States 
Area:
Neuroscience Biology, Cell Biology
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"Meir Scheinfeld"
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Luciano D'Adamio grad student 2005 Yeshiva University
 (The interaction between AbetaPP and JIP1 as a mechanism for linking transcriptional activation and the JNK stress pathway to Alzheimer's disease pathogenesis.)
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Publications

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D'Ambrosio C, Arena S, Fulcoli G, et al. (2006) Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease. Molecular & Cellular Proteomics : McP. 5: 97-113
Scheinfeld MH, Ghersi E, Davies P, et al. (2003) Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. The Journal of Biological Chemistry. 278: 42058-63
Scheinfeld MH, Matsuda S, D'Adamio L. (2003) JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65. Proceedings of the National Academy of Sciences of the United States of America. 100: 1729-34
Scheinfeld MH, Ghersi E, Laky K, et al. (2002) Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription. The Journal of Biological Chemistry. 277: 44195-201
Tarr PE, Contursi C, Roncarati R, et al. (2002) Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Biochemical and Biophysical Research Communications. 295: 324-9
Roncarati R, Sestan N, Scheinfeld MH, et al. (2002) The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 7102-7
Scheinfeld MH, Roncarati R, Vito P, et al. (2002) Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP). The Journal of Biological Chemistry. 277: 3767-75
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