Matt Trudeau, Ph.D.

Affiliations: 
Physiology University of Maryland School of Medicine, Baltimore, MD, United States 
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"Matt Trudeau"
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Publications

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Liu QN, Trudeau MC. (2015) Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Plos One. 10: e0123951
Jones DK, Liu F, Vaidyanathan R, et al. (2014) hERG 1b is critical for human cardiac repolarization. Proceedings of the National Academy of Sciences of the United States of America. 111: 18073-7
Gianulis EC, Liu Q, Trudeau MC. (2013) Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels. The Journal of General Physiology. 142: 351-66
Brelidze TI, Gianulis EC, DiMaio F, et al. (2013) Structure of the C-terminal region of an ERG channel and functional implications. Proceedings of the National Academy of Sciences of the United States of America. 110: 11648-53
Gustina AS, Trudeau MC. (2013) The eag domain regulates hERG channel inactivation gating via a direct interaction. The Journal of General Physiology. 141: 229-41
Trudeau MC. (2012) Unlocking the mechanisms of HCN channel gating with locked-open and locked-closed channels. The Journal of General Physiology. 140: 457-61
Gustina AS, Trudeau MC. (2012) HERG potassium channel regulation by the N-terminal eag domain. Cellular Signalling. 24: 1592-8
Trudeau MC, Leung LM, Roti ER, et al. (2011) hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome. The Journal of General Physiology. 138: 581-92
Gianulis EC, Trudeau MC. (2011) Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels. The Journal of Biological Chemistry. 286: 22160-9
Gustina AS, Trudeau MC. (2011) hERG potassium channel gating is mediated by N- and C-terminal region interactions. The Journal of General Physiology. 137: 315-25
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