Yasser Heakal, Ph.D.

Affiliations: 
2009 Pennsylvania State University, State College, PA, United States 
Area:
Pharmacology
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"Yasser Heakal"
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Mark Kester grad student 2009 Penn State
 (Identification of novel pharmacological approaches to inhibit neurotensin receptor -1 mitogenic signaling in breast cancer cells.)
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Publications

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Heakal Y, Kester M, Savage S. (2011) Vemurafenib (PLX4032): an orally available inhibitor of mutated BRAF for the treatment of metastatic melanoma. The Annals of Pharmacotherapy. 45: 1399-405
Jiang Y, DiVittore NA, Kaiser JM, et al. (2011) Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer. Cancer Biology & Therapy. 12: 574-85
Heakal Y, Woll MP, Fox T, et al. (2011) Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains. Cancer Biology & Therapy. 12: 427-35
Heakal Y, Kester M. (2009) Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells. Molecular Cancer Research : McR. 7: 724-34
Kester M, Heakal Y, Fox T, et al. (2008) Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells. Nano Letters. 8: 4116-21
Zolnik BS, Stern ST, Kaiser JM, et al. (2008) Rapid distribution of liposomal short-chain ceramide in vitro and in vivo. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1709-15
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