Rebecca J. Fairclough, D.Phil.

Affiliations: 
Physiology, Anatomy and Genetics University of Oxford, Oxford, United Kingdom 
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"Rebecca Fairclough"
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Publications

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Vuorinen A, Wilkinson IVL, Chatzopoulou M, et al. (2021) Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. European Journal of Medicinal Chemistry. 220: 113431
Fairclough RJ, Wood MJ, Davies KE. (2013) Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches. Nature Reviews. Genetics. 14: 373-8
Fairclough RJ, Perkins KJ, Davies KE. (2012) Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy. Current Gene Therapy. 12: 206-44
Fairclough RJ, Bareja A, Davies KE. (2011) Progress in therapy for Duchenne muscular dystrophy. Experimental Physiology. 96: 1101-13
Tinsley JM, Fairclough RJ, Storer R, et al. (2011) Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse. Plos One. 6: e19189
Grigorieva IV, Mirczuk S, Gaynor KU, et al. (2010) Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. The Journal of Clinical Investigation. 120: 2144-55
Li D, Bareja A, Judge L, et al. (2010) Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. Journal of Cell Science. 123: 2008-13
Vanoevelen J, Dode L, Van Baelen K, et al. (2005) The secretory pathway Ca2+/Mn2+-ATPase 2 is a Golgi-localized pump with high affinity for Ca2+ ions. The Journal of Biological Chemistry. 280: 22800-8
Fairclough RJ, Lonie L, Van Baelen K, et al. (2004) Hailey-Hailey disease: identification of novel mutations in ATP2C1 and effect of missense mutation A528P on protein expression levels. The Journal of Investigative Dermatology. 123: 67-71
Dhitavat J, Fairclough RJ, Hovnanian A, et al. (2004) Calcium pumps and keratinocytes: lessons from Darier's disease and Hailey-Hailey disease. The British Journal of Dermatology. 150: 821-8
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