Donald M. Hilvert
Affiliations: | Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland |
Area:
chemical biologyWebsite:
http://www.protein.ethz.ch/hilvert.htmlGoogle:
"Donald Hilvert"Mean distance: 6.6 | S | N | B | C | P |
Parents
Sign in to add mentor| Ronald Charles David Breslow | grad student | 1983 | Columbia | |
| (Enzyme Mechanisms & Models. Part I. Evidence for the General-Base Mechanism in Carboxypeptidase A-catalyzed Reactions. Part II. Thiazolium-Cyclodextrins as Holoenzyme Mimics of Thiamin-dependent Enzymes) | ||||
| Emil Thomas Kaiser | post-doc | Rockefeller | ||
Children
Sign in to add trainee| Joris Beld | grad student | ETH/Uni Zurich | |
| Gavin MacBeath | grad student | 1997 | Scripps Institute |
| Zhaohui Sunny Zhou | grad student | 1991-1997 | Scripps Institute |
| Kinya Hotta | grad student | 2001 | Scripps Institute |
| Anthony P. Green | post-doc | ETH Zürich | |
| Kenneth J. Woycechowsky | post-doc | ETH/Uni Zurich (STSTree) | |
| J. Gerard Roelfes | post-doc | 2003 | ETH Zürich |
| Andreas Herrmann | post-doc | 2002-2003 | ETH Zürich |
| Norman Metanis | post-doc | 2008-2013 | ETH Zürich |
| Zbigniew Pianowski | post-doc | 2008-2014 | ETH Zürich |
| Vladimir Torbeev | post-doc | 2010-2014 | ETH Zürich |
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Publications
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| Kipnis Y, Chaib AO, Vorobieva AA, et al. (2022) Design and optimization of enzymatic activity in a de novo β-barrel scaffold. Protein Science : a Publication of the Protein Society. 31: e4405 |
| Lovelock SL, Crawshaw R, Basler S, et al. (2022) The road to fully programmable protein catalysis. Nature. 606: 49-58 |
| Basler S, Studer S, Zou Y, et al. (2021) Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold. Nature Chemistry |
| Otten R, Pádua RAP, Bunzel HA, et al. (2020) How directed evolution reshapes the energy landscape in an enzyme to boost catalysis. Science (New York, N.Y.) |
| Macdonald DS, Hilvert D. (2020) Enhancing promiscuous chemistries of a Schiff-base forming enzyme by divergent evolution. Methods in Enzymology. 644: 95-120 |
| Tinzl M, Hilvert D. (2020) Trapping transient protein species by genetic code expansion Chembiochem |
| Russ WP, Figliuzzi M, Stocker C, et al. (2020) An evolution-based model for designing chorismate mutase enzymes. Science (New York, N.Y.). 369: 440-445 |
| Macdonald DS, Garrabou X, Klaus C, et al. (2020) Engineered artificial carboligases facilitate regioselective preparation of enantioenriched aldol adducts. Journal of the American Chemical Society |
| Tytgat HLP, Lin CW, Levasseur MD, et al. (2019) Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies. Nature Communications. 10: 5403 |
| Weitzner BD, Kipnis Y, Daniel AG, et al. (2019) A computational method for design of connected catalytic networks in proteins. Protein Science : a Publication of the Protein Society |