Nicholas J. Pantazis

University of Iowa, Iowa City, IA 
Neuroscience Biology, Physiology Biology
"Nicholas Pantazis"
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Kouzoukas DE, Bhalla RC, Pantazis NJ. (2018) Activation of cyclic GMP-dependent protein kinase blocks alcohol-mediated cell death and calcium disruption in cerebellar granule neurons. Neuroscience Letters. 676: 108-112
Kouzoukas DE, Li G, Takapoo M, et al. (2013) Intracellular calcium plays a critical role in the alcohol-mediated death of cerebellar granule neurons. Journal of Neurochemistry. 124: 323-35
Li Q, Spencer NY, Pantazis NJ, et al. (2011) Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity. The Journal of Biological Chemistry. 286: 40151-62
Karaçay B, Li G, Pantazis NJ, et al. (2007) Stimulation of the cAMP pathway protects cultured cerebellar granule neurons against alcohol-induced cell death by activating the neuronal nitric oxide synthase (nNOS) gene. Brain Research. 1143: 34-45
Bonthius DJ, McKim RA, Koele L, et al. (2006) Severe alcohol-induced neuronal deficits in the hippocampus and neocortex of neonatal mice genetically deficient for neuronal nitric oxide synthase (nNOS). The Journal of Comparative Neurology. 499: 290-305
Bonthius DJ, McKim R, Koele L, et al. (2004) Use of frozen sections to determine neuronal number in the murine hippocampus and neocortex using the optical disector and optical fractionator. Brain Research. Brain Research Protocols. 14: 45-57
Bonthius DJ, Karacay B, Dai D, et al. (2004) The NO-cGMP-PKG pathway plays an essential role in the acquisition of ethanol resistance by cerebellar granule neurons. Neurotoxicology and Teratology. 26: 47-57
Hutton Kahrberg AM, Pantazis NJ, McKim RA, et al. (2004) A Nitric Oxide Signaling Pathway Protects the Developing Brain against Alcohol-induced Neuronal Death Comprehensive Handbook of Alcohol Related Pathology. 2: 871-885
Bonthius DJ, Karacay B, Dai D, et al. (2003) FGF-2, NGF and IGF-1, but not BDNF, utilize a nitric oxide pathway to signal neurotrophic and neuroprotective effects against alcohol toxicity in cerebellar granule cell cultures. Brain Research. Developmental Brain Research. 140: 15-28
Bonthius DJ, Tzouras G, Karacay B, et al. (2002) Deficiency of neuronal nitric oxide synthase (nNOS) worsens alcohol-induced microencephaly and neuronal loss in developing mice. Brain Research. Developmental Brain Research. 138: 45-59
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