Shaji Theodore, Ph.D.

Affiliations: 
2006 University of Kentucky, Lexington, KY 
Area:
Toxicology, Neuroscience Biology, Virology Biology
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"Shaji Theodore"
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Parents

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William F. Maragos grad student 2006 University of Kentucky
 (Human immunodeficiency virus-1 protein Tat and methamphetamine interactions in the rat basal ganglia.)
David G. Standaert post-doc 2006-2009 UAB
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Publications

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Theodore S, Maragos W. (2015) 6-Hydroxydopamine as a tool to understand adaptive immune system-induced dopamine neurodegeneration in Parkinson's disease. Immunopharmacology and Immunotoxicology. 37: 393-9
Theodore S, Cass WA, Dwoskin LP, et al. (2012) HIV-1 protein Tat inhibits vesicular monoamine transporter-2 activity in rat striatum. Synapse (New York, N.Y.). 66: 755-7
Cao S, Theodore S, Standaert DG. (2010) Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease. Molecular Neurodegeneration. 5: 42
Theodore S, Cao S, McLean PJ, et al. (2008) Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease. Journal of Neuropathology and Experimental Neurology. 67: 1149-58
Theodore S, Cass WA, Nath A, et al. (2007) Progress in understanding basal ganglia dysfunction as a common target for methamphetamine abuse and HIV-1 neurodegeneration. Current Hiv Research. 5: 301-13
Theodore S, Stolberg S, Cass WA, et al. (2006) Human immunodeficiency virus-1 protein tat and methamphetamine interactions. Annals of the New York Academy of Sciences. 1074: 178-90
Theodore S, Cass WA, Nath A, et al. (2006) Inhibition of tumor necrosis factor-alpha signaling prevents human immunodeficiency virus-1 protein Tat and methamphetamine interaction. Neurobiology of Disease. 23: 663-8
Theodore S, Cass WA, Maragos WF. (2006) Involvement of cytokines in human immunodeficiency virus-1 protein Tat and methamphetamine interactions in the striatum. Experimental Neurology. 199: 490-8
Theodore S, Cass WA, Maragos WF. (2006) Methamphetamine and human immunodeficiency virus protein Tat synergize to destroy dopaminergic terminals in the rat striatum. Neuroscience. 137: 925-35
Orren DK, Theodore S, Machwe A. (2002) The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro. Biochemistry. 41: 13483-8
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