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Jonathan E. Harms, Ph.D.

Affiliations: 
2013 Biomedical Sciences Colorado State University, Fort Collins, CO 
Area:
Neuroscience Biology, General Biophysics
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"Jonathan Harms"
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Kathryn Partin grad student 2013 Colorado State
 (Structure-function relationships underlying GluA2 mechanisms of deactivation, desensitization, and modulation.)

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Publications

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Caldwell N, Harms JE, Partin KM, et al. (2015) Rational Design of a Novel AMPA Receptor Modulator through a Hybridization Approach. Acs Medicinal Chemistry Letters. 6: 392-6
Weeks AM, Harms JE, Partin KM, et al. (2014) Functional insight into development of positive allosteric modulators of AMPA receptors. Neuropharmacology. 85: 57-66
Harms JE, Benveniste M, Kessler M, et al. (2014) A charge-inverting mutation in the "linker" region of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors alters agonist binding and gating kinetics independently of allosteric modulators. The Journal of Biological Chemistry. 289: 10702-14
Harms JE, Benveniste M, Maclean JK, et al. (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology. 64: 45-52
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