Haibing Jiang, Ph.D.

Affiliations: 
2003 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacology
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"Haibing Jiang"
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Parents

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Donald B. DeFranco grad student 2003 University of Pittsburgh
 (Mechanisms of polyglutamine expanded huntingtin induced toxicity.)
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Publications

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Liu J, Li T, Thomas JM, et al. (2016) Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models. Human Molecular Genetics
Scharadin TM, Jiang H, Jans R, et al. (2011) TIG3 tumor suppressor-dependent organelle redistribution and apoptosis in skin cancer cells. Plos One. 6: e23230
Liang Y, Jiang H, Ratovitski T, et al. (2009) ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line. Brain Research. 1286: 221-9
Ratovitski T, Gucek M, Jiang H, et al. (2009) Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells. The Journal of Biological Chemistry. 284: 10855-67
Ko HS, Bailey R, Smith WW, et al. (2009) CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proceedings of the National Academy of Sciences of the United States of America. 106: 2897-902
Eckert RL, Sturniolo MT, Jans R, et al. (2009) TIG3: a regulator of type I transglutaminase activity in epidermis. Amino Acids. 36: 739-46
Liu Z, Wang X, Yu Y, et al. (2008) A Drosophila model for LRRK2-linked parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2693-8
Smith WW, Pei Z, Jiang H, et al. (2006) Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nature Neuroscience. 9: 1231-3
Jiang H, Poirier MA, Liang Y, et al. (2006) Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin. Neurobiology of Disease. 23: 543-51
Smith WW, Pei Z, Jiang H, et al. (2005) Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 18676-81
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