Jennifer Tran, Ph.D.

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology
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Parents

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Robert S. Kerbel grad student 2004 University of Toronto
 (Sensitizing tumor vascular endothelial cells to anti-angiogenic therapy.)
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Publications

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Syed ZA, Tran JA, Jurkunas UV. (2017) Peripheral Endothelial Cell Count Is a Predictor of Disease Severity in Advanced Fuchs Endothelial Corneal Dystrophy. Cornea
Voskas D, Jones N, Van Slyke P, et al. (2005) A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice. The American Journal of Pathology. 166: 843-55
Master Z, Tran J, Bishnoi A, et al. (2003) Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization. The Journal of Biological Chemistry. 278: 30170-9
Jones N, Chen SH, Sturk C, et al. (2003) A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function. Molecular and Cellular Biology. 23: 2658-68
Ebos JM, Tran J, Master Z, et al. (2002) Imatinib mesylate (STI-571) reduces Bcr-Abl-mediated vascular endothelial growth factor secretion in chronic myelogenous leukemia. Molecular Cancer Research : McR. 1: 89-95
Tran J, Master Z, Yu JL, et al. (2002) A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proceedings of the National Academy of Sciences of the United States of America. 99: 4349-54
Kerbel RS, Yu J, Tran J, et al. (2001) Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches. Cancer Metastasis Reviews. 20: 79-86
Master Z, Jones N, Tran J, et al. (2001) Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. The Embo Journal. 20: 5919-28
Tran J, Rak J, Sheehan C, et al. (1999) Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochemical and Biophysical Research Communications. 264: 781-8
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