Shizhang Ling, Ph.D.

Affiliations: 
2004 University of Calgary, Calgary, Alberta, Canada 
Area:
Neuroscience Biology
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"Shizhang Ling"
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Andrew P. Braun grad student 2004 University of Calgary
 (Regulation of large conductance calcium -activated potassium channel by protein tyrosine phosphorylation and SNARE protein syntaxin 1A.)
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Publications

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Leonard B, Humtsoe JO, Kim H, et al. (2017) Abstract 64: Abnormal splicing events in adenoid cystic carcinoma Clinical Cancer Research. 23: 64-64
Izumchenko E, Chang X, Michailidi C, et al. (2014) The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors. Cancer Research. 74: 3995-4005
Chang X, Izumchenko E, Solis LM, et al. (2013) The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors. Plos One. 8: e68966
Brait M, Ling S, Nagpal JK, et al. (2012) Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers. Plos One. 7: e44951
Ling S, Chang X, Schultz L, et al. (2011) An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer. Cancer Research. 71: 3812-21
Yang Y, Wu X, Gui P, et al. (2010) Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation. The Journal of Biological Chemistry. 285: 131-41
Ling S, Chang X, Lee T, et al. (2010) Abstract 5171: EGFR induction of SOX9 is required in a cellular migration program induced by urothelial injury and maintained in cancer Cancer Research. 70: 5171-5171
Gui P, Wu X, Ling S, et al. (2006) Integrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and protein kinase A pathways. The Journal of Biological Chemistry. 281: 14015-25
Sheng JZ, Weljie A, Sy L, et al. (2005) Homology modeling identifies C-terminal residues that contribute to the Ca2+ sensitivity of a BKCa channel. Biophysical Journal. 89: 3079-92
Ling S, Sheng JZ, Braun AP. (2004) The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. American Journal of Physiology. Cell Physiology. 287: C698-706
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